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NR1H4 [nucleoplasm]
Stable Identifier
R-MMU-5340228
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
Q60641
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Nuclear Receptor transcription pathway (Mus musculus)
Formation of NR-MED1 Coactivator Complex (Mus musculus)
NR [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
NR-MED1 Coactivator Complex [nucleoplasm] (Mus musculus)
NR [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Formation of NR-NCOR Corepressor Complex (Mus musculus)
NR [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
NR-NCOR CoRepressor Complex [nucleoplasm] (Mus musculus)
NR [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP7A1 7-hydroxylates CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
CYP7B1 7-hydroxylates 25OH-CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Recycling of bile acids and salts (Mus musculus)
NR1H4 binds DCA, CDCA, LCHA (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Synthesis of bile acids and bile salts (Mus musculus)
CYP7B1 7-hydroxylates 25OH-CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Mus musculus)
27-hydroxycholesterol is 7alpha-hydroxylated (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
CYP7A1 7-hydroxylates CHOL (Mus musculus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of intracellular receptors (Mus musculus)
SUMOylation of NR1H4 with SUMO1 (Mus musculus)
NR1H4:chenodeoxycholate [nucleoplasm] (Mus musculus)
NR1H4 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q60641
Reference Genes
BioGPS Gene:20186
ENSEMBL:ENSMUSG00000047638
ENSEMBL:ENSMUSG00000047638.16
KEGG Gene (Mus musculus):20186
Monarch:20186
NCBI Gene:20186
UCSC:Q60641
Reference Transcript
RefSeq:XM_006513393.3
RefSeq:NM_001163700.1
RefSeq:XM_006513391.3
RefSeq:NM_001163504.1
Other Identifiers
10371784
1419105_at
17244070
20186
4313000
4317854
4401282
4404846
4510524
4529232
4680648
4734934
4778637
5067412
5107647
5189753
5337809
5463675
5580354
5589752
97969_at
A_51_P464669
A_55_P2369474
GE33607
GO:0000122
GO:0000785
GO:0000791
GO:0000976
GO:0000977
GO:0000978
GO:0000981
GO:0001080
GO:0001221
GO:0001228
GO:0001678
GO:0002376
GO:0003677
GO:0003690
GO:0003700
GO:0004879
GO:0005515
GO:0005634
GO:0005694
GO:0005975
GO:0006109
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006520
GO:0006629
GO:0006954
GO:0007043
GO:0007219
GO:0008206
GO:0008270
GO:0008289
GO:0010628
GO:0010804
GO:0010868
GO:0010903
GO:0010988
GO:0012501
GO:0015721
GO:0023052
GO:0030154
GO:0030522
GO:0032052
GO:0032088
GO:0032689
GO:0032692
GO:0032703
GO:0032715
GO:0032720
GO:0032740
GO:0032966
GO:0034162
GO:0034255
GO:0034330
GO:0035356
GO:0035774
GO:0038181
GO:0038183
GO:0038185
GO:0042277
GO:0042593
GO:0042632
GO:0042742
GO:0043066
GO:0043124
GO:0043226
GO:0043235
GO:0043565
GO:0044877
GO:0045087
GO:0045893
GO:0045944
GO:0046628
GO:0046872
GO:0046965
GO:0048856
GO:0050728
GO:0055089
GO:0060089
GO:0061178
GO:0070328
GO:0071222
GO:0071398
GO:0071417
GO:0071466
GO:0071638
GO:0071873
GO:0071941
GO:0098542
GO:0140110
GO:1902122
GO:1903413
GO:1904179
GO:1905695
GO:2000213
GO:2001250
ILMN_2727013
U09416_s_at
mMC009187
Participates
as a component of
NR1H4:chenodeoxycholate [nucleoplasm] (Mus musculus)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Mus musculus)
as an input of
NR1H4 binds DCA, CDCA, LCHA (Mus musculus)
as a member of
NR [nucleoplasm] (Mus musculus)
Other forms of this molecule
SUMO1-K132,K289-NR1H4 [nucleoplasm]
Inferred From
NR1H4 [nucleoplasm]
(Homo sapiens)
NR1H4-1 [nucleoplasm]
(Homo sapiens)
NR1H4-3 [nucleoplasm]
(Homo sapiens)
NR1H4-2 [nucleoplasm]
(Homo sapiens)
NR1H4-4 [nucleoplasm]
(Homo sapiens)
Cross References
ZINC - Investigational
NR1H4_MOUSE
RefSeq
XP_006513456.1
,
NP_001157172.1
,
NP_001156976.1
,
XP_006513454.1
ZINC - Substances
NR1H4_MOUSE
ZINC target
Q60641
Ensembl
ENSMUST00000058126
,
ENSMUSG00000047638
,
ENSMUST00000105297
,
ENSMUSP00000053092
,
ENSMUSP00000100934
,
ENSMUSP00000100933
,
ENSMUST00000105296
PRO
Q60641
ZINC - Predictions - Purchasable
NR1H4_MOUSE
MGI
1352464
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