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Derl2 [endoplasmic reticulum membrane]
Stable Identifier
R-MMU-5362350
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
endoplasmic reticulum membrane
Synonyms
DERL2, Q8BNI4
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Hedgehog (Mus musculus)
Hedgehog ligand biogenesis (Mus musculus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Mus musculus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
SYVN1 ubiquitinates Hh C-terminal fragments (Mus musculus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Mus musculus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Mus musculus)
ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
DERL oligomer [endoplasmic reticulum membrane] (Mus musculus)
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
DERL oligomer [endoplasmic reticulum membrane] (Mus musculus)
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Mus musculus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
DERL oligomer [endoplasmic reticulum membrane] (Mus musculus)
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
DERL oligomer [endoplasmic reticulum membrane] (Mus musculus)
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Mus musculus)
ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
DERL oligomer [endoplasmic reticulum membrane] (Mus musculus)
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
ERAD complex [endoplasmic reticulum membrane] (Mus musculus)
DERL oligomer [endoplasmic reticulum membrane] (Mus musculus)
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Derl2 [endoplasmic reticulum membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8BNI4
Gene Names
Derl2
Reference Genes
BioGPS Gene:116891 Derl2
ENSEMBL:ENSMUSG00000018442
KEGG:mmu:116891 Derl2
Monarch:116891 Derl2
NCBI Gene:116891 Derl2
UCSC:Q8BNI4 Derl2
Reference Transcript
RefSeq:NM_001291148.1 Derl2
RefSeq:NM_033562.4 Derl2
RefSeq:NM_001291147.1 Derl2
RefSeq:NM_001291146.1 Derl2
Other Identifiers
10388033
116891
1435101_at
1448438_at
160769_at
163577_at
17265451
4340442
4382299
4403820
4416134
4503215
4505218
4522124
4527717
4602646
4709711
4718343
4767012
4786916
4806281
4853236
4857009
4902156
4917508
5033748
5086581
5152581
5190318
5346320
5368476
5397815
5447566
5492415
5603830
A_51_P498831
A_52_P84275
A_55_P2178203
GE41918
GO:0001967
GO:0005047
GO:0005515
GO:0005768
GO:0005769
GO:0005770
GO:0005783
GO:0005789
GO:0006886
GO:0006950
GO:0006986
GO:0008284
GO:0010498
GO:0016020
GO:0030163
GO:0030307
GO:0030968
GO:0030970
GO:0031410
GO:0036503
GO:0043226
GO:0044877
GO:1904153
ILMN_1241323
ILMN_2588673
ILMN_2685124
ILMN_2685125
aa104485_s_at
mMC020999
mMR029600
Participates
as a component of
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Mus musculus)
as a candidate of
DERLs [endoplasmic reticulum membrane] (Mus musculus)
Inferred From
DERL2 [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
ENSEMBL
ENSMUSG00000018442
,
ENSMUSP00000104163
,
ENSMUST00000143850
,
ENSMUST00000108523
,
ENSMUSP00000117052
PRO
Q8BNI4
MGI
2151483
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