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Sufu [cytosol]
Stable Identifier
R-MMU-5610427
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Hedgehog (Mus musculus)
Hedgehog 'off' state (Mus musculus)
Degradation of GLI1 by the proteasome (Mus musculus)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Mus musculus)
Sufu [cytosol] (Mus musculus)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Mus musculus)
Sufu [cytosol] (Mus musculus)
GLI proteins bind SUFU (Mus musculus)
GLI:SUFU [cytosol] (Mus musculus)
Sufu [cytosol] (Mus musculus)
Sufu [cytosol] (Mus musculus)
GLI3 is processed to GLI3R by the proteasome (Mus musculus)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Mus musculus)
Sufu [cytosol] (Mus musculus)
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Mus musculus)
GLI:SUFU [cytosol] (Mus musculus)
Sufu [cytosol] (Mus musculus)
Hedgehog 'on' state (Mus musculus)
GLI proteins bind SUFU (Mus musculus)
GLI:SUFU [cytosol] (Mus musculus)
Sufu [cytosol] (Mus musculus)
Sufu [cytosol] (Mus musculus)
GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Mus musculus)
GLI:SUFU [cytosol] (Mus musculus)
Sufu [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9Z0P7 Sufu
Gene Names
Sufu
Chain
chain:1-484
Reference Genes
BioGPS Gene:24069 Sufu
ENSEMBL:ENSMUSG00000025231.18 Sufu
KEGG Gene (Mus musculus):24069 Sufu
Monarch:24069 Sufu
NCBI Gene:24069 Sufu
UCSC:Q9Z0P7 Sufu
Reference Transcript
RefSeq:NM_001025391.2 Sufu
RefSeq:NM_015752.3 Sufu
Other Identifiers
10463645
109673_at
1420848_at
1450024_at
17360022
24069
4345865
4351333
4366759
4435748
4449236
4692382
4765862
4785349
4830402
4989563
5024463
5045336
5066395
5217460
5228679
5255272
5312691
5343120
5350417
5406011
5414718
5607032
A_51_P396550
A_52_P340811
A_52_P603184
GE36933
GO:0000122
GO:0001843
GO:0001947
GO:0003281
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005929
GO:0006351
GO:0006355
GO:0007224
GO:0007286
GO:0007368
GO:0008013
GO:0008134
GO:0019901
GO:0021513
GO:0021775
GO:0021776
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0035904
GO:0043226
GO:0043588
GO:0045879
GO:0048856
GO:0060976
GO:1990788
GO:2000059
GO:2001040
ILMN_2441176
ILMN_2636718
ILMN_3127458
mMC002219
mMR027979
Participates
as a component of
ub-p11S-Gli2:Sufu [cytosol] (Mus musculus)
p11S-Gli2:Sufu [cytosol] (Mus musculus)
p8S-Gli2:Sufu [cytosol] (Mus musculus)
p4S-Gli2:Sufu [cytosol] (Mus musculus)
Gli2:Sufu [cytosol] (Mus musculus)
pS-GLI1-Sufu [cytosol] (Homo sapiens)
GLI1-Sufu [cytosol] (Homo sapiens)
GLI:SUFU [cytosol] (Mus musculus)
as an output of
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Mus musculus)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Mus musculus)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Mus musculus)
as an input of
GLI proteins bind SUFU (Mus musculus)
Other forms of this molecule
Sufu [ciliary tip]
Sufu [ciliary base]
Inferred From
SUFU [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001020562.1
,
NP_056567.2
Ensembl
ENSMUSG00000025231
,
ENSMUSP00000049109
,
ENSMUSP00000107498
,
ENSMUST00000111867
,
ENSMUST00000039922
PRO
Q9Z0P7
MGI
1345643
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O55128 Sap18
2
Sap18 [nucleoplasm]
(R-MMU-573349)
Sap18 [nucleoplasm]
(R-MMU-351694)
0.59
6
UniProt:P16110 Lgals3
4
LGALS3 [ficolin-1-rich granule membrane]
(R-MMU-6803307)
LGALS3 [plasma membrane]
(R-MMU-879445)
LGALS3 [secretory granule membrane]
(R-MMU-6803327)
Lgals3 [extracellular region]
(R-MMU-8878612)
0.557
5
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