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Wdr5 [nucleoplasm]
Stable Identifier
R-MMU-5619358
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
WD repeat-containing protein 5, WDR5_MOUSE
Locations in the PathwayBrowser for interactor UniProt:P20263 Pou5f1
Expand all
Chromatin organization (Mus musculus)
Chromatin modifying enzymes (Mus musculus)
RMTs methylate histone arginines (Mus musculus)
WDR5 binds Me2sR3-replicative histone H3 (Mus musculus)
Wdr5 [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
Epigenetic regulation of gene expression (Mus musculus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Mus musculus)
Formation of WDR5-containing histone-modifying complexes (Mus musculus)
Formation of the GCN5-ATAC complex (Mus musculus)
Wdr5 [nucleoplasm] (Mus musculus)
Formation of the NSL complex (Mus musculus)
Wdr5 [nucleoplasm] (Mus musculus)
Formation of the PCAF-ATAC complex (Mus musculus)
Wdr5 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:P61965 Wdr5
Gene Names
Wdr5, Big, Big3
Chain
initiator methionine:, chain:2-334
Reference Genes
BioGPS Gene:140858 Wdr5
ENSEMBL:ENSMUSG00000026917.16 Wdr5
KEGG Gene (Mus musculus):140858 Wdr5
Monarch:140858 Wdr5
NCBI Gene:140858 Wdr5
UCSC:P61965 Wdr5
Reference Transcript
RefSeq:XM_006497672.3 Wdr5
RefSeq:NM_080848.2 Wdr5
Other Identifiers
10470427
140858
1416581_at
1448389_at
17368526
4365029
4416237
4474787
4565634
4764583
4801539
4879791
4905015
4945373
5102108
5195247
5221442
5226610
5318366
5382457
5481731
5545836
5559242
5566851
97845_at
A_51_P390437
A_52_P7154
A_55_P1994917
GE42286
GO:0000122
GO:0000123
GO:0001501
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005856
GO:0005975
GO:0006094
GO:0006325
GO:0006351
GO:0006355
GO:0006357
GO:0016740
GO:0030154
GO:0031175
GO:0035064
GO:0035097
GO:0036211
GO:0042393
GO:0042800
GO:0043226
GO:0044545
GO:0044665
GO:0044666
GO:0045722
GO:0045815
GO:0045893
GO:0045995
GO:0048188
GO:0048856
GO:0051302
GO:0051571
GO:0051726
GO:0071339
GO:0072686
GO:0090043
GO:0140096
GO:0140672
ILMN_2426921
aa039038_s_at
mMC005953
Participates
as a member of
DCAF protein [nucleoplasm] (Mus musculus)
as an input of
Formation of the NSL complex (Mus musculus)
Eomes, Wdr5, Kat2a, Tbxt bind the Mesp1 gene (Mus musculus)
Formation of the GCN5-ATAC complex (Mus musculus)
Formation of the PCAF-ATAC complex (Mus musculus)
WDR5 binds Me2sR3-replicative histone H3 (Mus musculus)
as a component of
NSL (PHF20L1) [nucleoplasm] (Mus musculus)
mWRAD complex [nucleoplasm] (Mus musculus)
Eomes:Wdr5:Kat2a:Tbxt:Mesp1 gene [nucleoplasm] (Mus musculus)
NSL (PHF20) [nucleoplasm] (Mus musculus)
GCN5-ATAC complex [nucleoplasm] (Mus musculus)
PCAF-ATAC complex [nucleoplasm] (Mus musculus)
WDR5:Me2sR3-histone H3 [nucleoplasm] (Mus musculus)
Mll2,3 complex [nucleoplasm] (Mus musculus)
WRAD complex [nucleoplasm] (Mus musculus)
Inferred From
WDR5 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_543124.1
,
XP_006497735.1
Ensembl
ENSMUSP00000109585
,
ENSMUSG00000026917
,
ENSMUST00000113952
PRO
P61965
MGI
2155884
PDB
2XL3
,
2XL2
,
8OK1
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8BX09 Rbbp5
1
Rbbp5 [nucleoplasm]
(R-MMU-5619352)
0.802
6
UniProt:P20263 Pou5f1
2
Pou5f1 [nucleoplasm]
(R-MMU-3245981)
POU5F1 [nucleoplasm]
(R-MMU-452472)
0.711
7
UniProt:Q91X20 Ash2l
2
Ash2l [nucleoplasm]
(R-MMU-5619343)
Ash2l [nucleoplasm]
(R-MMU-1629834)
0.656
3
UniProt:Q61066
1
Nr0b1 [nucleoplasm]
(R-MMU-3008626)
0.462
2
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