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Rack1 [cytosol]
Stable Identifier
R-MMU-5626956
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
GNB2L1, P68040
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
GNB2L1 binds IKKA:IKKB:NEMO (Mus musculus)
IKKA:IKKB:NEMO:GNB2L1 [cytosol] (Mus musculus)
Rack1 [cytosol] (Mus musculus)
Rack1 [cytosol] (Mus musculus)
TNFR1-induced NF-kappa-B signaling pathway (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Mus musculus)
Rack1 [cytosol] (Mus musculus)
TNFR1-mediated ceramide production (Mus musculus)
TNF-α:TNFR1:NSMAF binds GNB2L1 (Mus musculus)
Rack1 [cytosol] (Mus musculus)
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Mus musculus)
Rack1 [cytosol] (Mus musculus)
TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Mus musculus)
TNF-alpha:TNFR1:NSMAF:GNB2L1:SMPD2,3 [plasma membrane] (Mus musculus)
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Mus musculus)
Rack1 [cytosol] (Mus musculus)
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Mus musculus)
Rack1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P68040
Gene Names
Rack1
Reference Genes
BioGPS Gene:14694 Rack1
ENSEMBL:ENSMUSG00000020372
ENSEMBL:ENSMUSG00000020372.16 Rack1
KEGG Gene (Mus musculus):14694 Rack1
Monarch:14694 Rack1
NCBI Gene:14694 Rack1
UCSC:P68040 Rack1
Reference Transcript
RefSeq:NM_008143.3 Rack1
Other Identifiers
10375487
1455168_a_at
14694
17248873
4445660
4450194
4672755
4988783
4993959
5172409
5319395
5335657
5341845
5374444
5414938
5497176
99340_at
A_51_P488673
A_52_P404108
GE34499
GO:0001891
GO:0001934
GO:0005080
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005829
GO:0005840
GO:0005886
GO:0006412
GO:0006417
GO:0006629
GO:0006915
GO:0007049
GO:0007163
GO:0007369
GO:0008104
GO:0008200
GO:0008656
GO:0010629
GO:0012501
GO:0015935
GO:0016020
GO:0016192
GO:0016567
GO:0017148
GO:0019899
GO:0019903
GO:0023052
GO:0030163
GO:0030178
GO:0030292
GO:0030308
GO:0030332
GO:0030335
GO:0030425
GO:0030496
GO:0030971
GO:0031334
GO:0032436
GO:0032880
GO:0033137
GO:0033209
GO:0034250
GO:0035556
GO:0035591
GO:0036211
GO:0038023
GO:0042169
GO:0042803
GO:0042995
GO:0042998
GO:0043005
GO:0043022
GO:0043025
GO:0043065
GO:0043204
GO:0043226
GO:0043473
GO:0043547
GO:0044297
GO:0045182
GO:0045834
GO:0045879
GO:0048471
GO:0048511
GO:0048856
GO:0048870
GO:0050765
GO:0051302
GO:0051434
GO:0051726
GO:0051898
GO:0051901
GO:0060089
GO:0060090
GO:0065003
GO:0071333
GO:0071363
GO:0072344
GO:0072659
GO:0098772
GO:1903076
GO:1903751
GO:1905038
GO:1990630
GO:1990904
GO:2000114
GO:2000543
GO:2001244
ILMN_2652645
Msa.1827.0_f_at
mMC016156
x75313_f_at
Participates
as an input of
TNF-α:TNFR1:NSMAF binds GNB2L1 (Mus musculus)
GNB2L1 binds IKKA:IKKB:NEMO (Mus musculus)
as a component of
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Mus musculus)
IKKA:IKKB:NEMO:GNB2L1 [cytosol] (Mus musculus)
This entity regulates
Negatively
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG
(Mus musculus)
Inferred From
GNB2L1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_032169.1
Ensembl
ENSMUST00000020640
,
ENSMUSG00000020372
,
ENSMUSP00000020640
PRO
P68040
MGI
101849
PDB
7LS2
,
7CPV
,
7LS1
,
7CPU
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8C5D8 Pias2
1
PIAS2-1 [nucleoplasm]
(R-MMU-2993785)
0.526
3
UniProt:Q62470
1
Itga3 [plasma membrane]
(R-MMU-204441)
0.499
3
UniProt:Q99LX0
5
Park7 [nucleoplasm]
(R-MMU-4085351)
Park7 [nucleoplasm]
(R-MMU-3900141)
Park7 [cytosol]
(R-MMU-9641100)
Park7 [cytosol]
(R-MMU-9641123)
Park7 [cytosol]
(R-MMU-9641128)
0.463
2
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