Reactome | Tnfrsf10b [plasma membrane]

Tnfrsf10b [plasma membrane]

Stable Identifier

R-MMU-5633393

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TNFRSF10A, Q9QZM4

Locations in the PathwayBrowser

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Programmed Cell Death (Mus musculus)

- Apoptosis (Mus musculus)
  - Caspase activation via extrinsic apoptotic signalling pathway (Mus musculus)
    - Caspase activation via Death Receptors in the presence of ligand (Mus musculus)
      - Dimerization of procaspase-8 (Mus musculus)
        
        TRAIL-mediated dimerization of procaspase-8 (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD:2xCASP8(1-479) [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
      - Regulation by c-FLIP (Mus musculus)
        
        Caspase-8 and FLIP(L) processing at DISC (Mus musculus)
        
        DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Mus musculus)
        
        DISC [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        DISC:procaspase-8:FLIP(L) [plasma membrane] (Mus musculus)
        
        DISC:procaspase-8 [plasma membrane] (Mus musculus)
        
        DISC [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479):CFLAR [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
- Regulated Necrosis (Mus musculus)
  - RIPK1-mediated regulated necrosis (Mus musculus)
    - Regulation of necroptotic cell death (Mus musculus)
      - CASP8 activity is inhibited (Mus musculus)
        
        FLIP(L) and procaspase-8 form heterodimer (Mus musculus)
        
        DISC:procaspase-8 [plasma membrane] (Mus musculus)
        
        DISC [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        DISC:procaspase-8:FLIP(L) [plasma membrane] (Mus musculus)
        
        DISC:procaspase-8 [plasma membrane] (Mus musculus)
        
        DISC [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        FLIP(S) and procaspase-8 form heterodimer (Mus musculus)
        
        DISC:procaspase-8 [plasma membrane] (Mus musculus)
        
        DISC [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)
        
        DISC:procaspase-8:FLIP(S) [plasma membrane] (Mus musculus)
        
        DISC:procaspase-8 [plasma membrane] (Mus musculus)
        
        DISC [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B:FADD [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B Trimer [plasma membrane] (Mus musculus)
        
        TNFSF10:TNFRSF10A,B [plasma membrane] (Mus musculus)
        
        Tnfrsf10b [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9QZM4

Gene Names

Tnfrsf10b

Reference Genes

ENSEMBL:ENSMUSG00000022074

UCSC:Q9QZM4 Tnfrsf10b

Other Identifiers

10416230

1421296_at

1422344_s_at

17301697

21933

4370524

4445528

4446276

4517719

4533374

4584459

4674593

4905882

5025950

5110463

5125436

5162925

5212775

5271573

5283108

5307038

5376308

5413378

5600547

A_52_P10134

A_52_P351638

A_55_P2027836

A_55_P2735845

GE38186

GO:0004888

GO:0005515

GO:0005886

GO:0006915

GO:0007165

GO:0008656

GO:0009986

GO:0016020

GO:0034976

GO:0036462

GO:0042981

GO:0043065

GO:0045569

GO:0051241

GO:0070059

ILMN_1230700

ILMN_2454348

ILMN_2455181

ILMN_2460875

ILMN_2945095

mMC017124

mMC021435

mMC023325

mMR026712

Participates

as an input of

as a component of

Other forms of this molecule

Tnfrsf10b [plasma membrane]

Inferred From

TNFRSF10A,TNFRSF10B [plasma membrane] (Homo sapiens)

TNFRSF10A [plasma membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSP00000022663, ENSMUSG00000022074, ENSMUST00000022663

PRO

Q9QZM4

MGI

1341090

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