Reactome | PARP1,PARP2 dimers [nucleoplasm]

PARP1,PARP2 dimers [nucleoplasm]

Stable Identifier

R-MMU-5649884

Type

Complex

Species

Mus musculus

Compartment

nucleoplasm

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 PARP1,PARP2 [nucleoplasm] (Mus musculus)

Participates

as an output of

PARG dePARylates PARP1,PARP2 (Mus musculus)

as an input of

PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Mus musculus)
PARP1 or PARP2 binds DDB2 at GG-NER site (Mus musculus)
PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Mus musculus)

as a component of

PARP1,PARP2:FEN1:POLB:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Mus musculus)
PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Mus musculus)
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Mus musculus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Mus musculus)

Inferred From

PARP1,PARP2 dimers [nucleoplasm] (Homo sapiens)

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