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mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
Stable Identifier
R-MMU-5653972
Type
Complex
Species
Mus musculus
Compartment
lysosomal membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
Active MTORC1 binds the ULK1 complex (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Active MTORC1 phosphorylates ULK1 (Mus musculus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Rheb in the MTORC1 complex hydrolyses GTP (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN gene transcription (Mus musculus)
MAF1 translocates to the nucleus (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 phosphorylates MAF1 (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
MTOR signalling (Mus musculus)
AKT1S1 (PRAS40) binds mTORC1 (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Mus musculus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Energy dependent regulation of mTOR by LKB1-AMPK (Mus musculus)
AMPK phosphorylates Raptor in the mTORC1 complex (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Formation of active mTORC1 complex (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 phosphorylates AKT1S1 (Mus musculus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1-mediated signalling (Mus musculus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mTORC1 [cytosol]
(Mus musculus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Mus musculus)
Participates
as an output of
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Mus musculus)
as an input of
Formation of active mTORC1 complex (Mus musculus)
as a component of
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
Inferred From
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Homo sapiens)
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