Expression of Npas2

Stable Identifier
R-MMU-5663263
Type
Reaction [omitted]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Expression of Npas2

The Npas2 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Transcription of Npas2 is enhanced by the Rora:Coactivator complex and repressed by the Nr1d1 (Rev-Erba):Corepressor complex.

Literature References
PubMed ID Title Journal Year
20817722 Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene

Crumbley, C, Wang, Y, Kojetin, DJ, Burris, TP

J Biol Chem 2010
17476214 Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism

Liu, C, Li, S, Liu, T, Borjigin, J, Lin, JD

Nature 2007
15199055 RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR

Lau, P, Nixon, SJ, Parton, RG, Muscat, GE

J Biol Chem 2004
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