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NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]
Stable Identifier
R-MMU-5668618
Type
Complex
Species
Mus musculus
Compartment
phagocytic vesicle membrane
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Innate Immune System (Mus musculus)
ROS and RNS production in phagocytes (Mus musculus)
NOX2 generates superoxide anion from oxygen (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate NADPH Oxidases (Mus musculus)
Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
RAC2:GTP binds NOX2 complex (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
RHO GTPase cycle (Mus musculus)
RAC2 GTPase cycle (Mus musculus)
RAC2 binds effectors at the phagocytic vesicle membrane (Mus musculus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
NOX2 complex [phagocytic vesicle membrane]
(Mus musculus)
RAC2:GTP [phagocytic vesicle membrane]
(Mus musculus)
Participates
as an output of
RAC2 binds effectors at the phagocytic vesicle membrane (Mus musculus)
RAC2:GTP binds NOX2 complex (Mus musculus)
as an input of
S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Mus musculus)
as a component of
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Mus musculus)
Inferred From
RAC2:GTP:RAC2 phagosome effectors [phagocytic vesicle membrane]
(Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]
(Homo sapiens)
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