Reactome | Nf2 [plasma membrane]

Nf2 [plasma membrane]

Stable Identifier

R-MMU-5669168

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

NF2, P46662

Locations in the PathwayBrowser for interactor UniProt:Q4VCS5%20AMOT

Expand all

External Reference Information

External Reference

UniProt:P46662

Gene Names

Nf2

Reference Genes

BioGPS Gene:18016 Nf2

ENSEMBL:ENSMUSG00000009073

ENSEMBL:ENSMUSG00000009073.17 Nf2

KEGG Gene (Mus musculus):18016 Nf2

Monarch:18016 Nf2

NCBI Gene:18016 Nf2

UCSC:P46662 Nf2

Reference Transcript

Other Identifiers

10383897

1421820_a_at

1427708_a_at

1450382_at

1451829_a_at

168494_f_at

17260036

18016

4322280

4338734

4378002

4415571

4527188

4750282

4817868

4857725

4909161

4927072

5005877

5050728

5123142

5155961

5210025

5223219

5229091

5268927

5361212

5416380

5424176

5449131

5476963

5482461

5526395

5573469

92643_at

A_52_P170339

A_52_P555913

A_55_P2423646

A_55_P2506875

GE35795

GO:0000165

GO:0001707

GO:0001726

GO:0003779

GO:0005178

GO:0005515

GO:0005634

GO:0005730

GO:0005737

GO:0005768

GO:0005769

GO:0005829

GO:0005856

GO:0005886

GO:0005912

GO:0007010

GO:0007155

GO:0007398

GO:0007420

GO:0008013

GO:0008092

GO:0008285

GO:0008360

GO:0010626

GO:0012501

GO:0014010

GO:0014013

GO:0016020

GO:0016192

GO:0019904

GO:0021766

GO:0022408

GO:0023052

GO:0030027

GO:0030036

GO:0030154

GO:0030175

GO:0030308

GO:0030864

GO:0031410

GO:0031647

GO:0032154

GO:0032991

GO:0033687

GO:0033689

GO:0034330

GO:0035330

GO:0036211

GO:0042127

GO:0042475

GO:0042532

GO:0042981

GO:0042995

GO:0043005

GO:0043226

GO:0043409

GO:0044297

GO:0045177

GO:0045216

GO:0045597

GO:0046426

GO:0048471

GO:0048856

GO:0050767

GO:0051496

GO:0051726

GO:0070306

GO:0072091

GO:0098858

GO:1900180

GO:1902115

GO:1902966

GO:2000177

GO:2000643

ILMN_1244011

ILMN_2611840

Msa.1016.0_s_at

l27090_at

l27090_g_at

mMC004176

Participates

as an input of

NF2 binds PAK1 (Mus musculus)

as a component of

PAK1:NF2 [plasma membrane] (Mus musculus)

This entity regulates

Negatively

RAC1 and CDC42 activate PAK1 (Mus musculus)

Inferred From

NF2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001239179.1, NP_035028.2, XP_011241971.1, NP_001239180.1, NP_001239181.1, XP_006514633.1, NP_001239182.1

Ensembl

ENSMUSG00000009073, ENSMUSP00000105536, ENSMUST00000109910, ENSMUSP00000055033, ENSMUST00000053079, ENSMUST00000056290, ENSMUSP00000055061

PRO

P46662

MGI

97307

PDB

4ZRK, 1ISN, 3WA0, 4P7I

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95835 LATS1	2	LATS1 [cytosol] (R-HSA-2028562) p-S909,T1079-LATS1 [cytosol] (R-HSA-2028551)	0.537	5
UniProt:Q4VCS5 AMOT			0.499	2