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KSR1 [cytosol]
Stable Identifier
R-MMU-5672587
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q61097
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
Negative regulation of MAPK pathway (Mus musculus)
BRAP binds KSR1:MARK3 (Mus musculus)
BRAP:KSR1:MARK3 [cytosol] (Mus musculus)
KSR1:MARK3 [cytosol] (Mus musculus)
KSR1 [cytosol] (Mus musculus)
KSR1:MARK3 [cytosol] (Mus musculus)
KSR1 [cytosol] (Mus musculus)
RAF activation (Mus musculus)
MARK3 phosphorylates KSR1 (Mus musculus)
KSR1:MARK3 [cytosol] (Mus musculus)
KSR1 [cytosol] (Mus musculus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Mus musculus)
BRAP:KSR1:MARK3 [cytosol] (Mus musculus)
KSR1:MARK3 [cytosol] (Mus musculus)
KSR1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q61097
Reference Genes
BioGPS Gene:16706
ENSEMBL:ENSMUSG00000018334
ENSEMBL:ENSMUSG00000018334.19
KEGG Gene (Mus musculus):16706
Monarch:16706
NCBI Gene:16706
UCSC:Q61097
Reference Transcript
RefSeq:NM_013571.3
RefSeq:XM_006532335.3
RefSeq:NM_001348207.1
Other Identifiers
10388914
117128_at
1419823_s_at
1450114_at
16706
17266534
4353954
4384997
4389876
4482449
4519878
4585955
4680703
4688210
4703865
4838946
4998697
5027654
5031293
5039608
5058447
5167029
5271013
5287882
5326132
5351235
5404598
5443883
5459002
5557908
5566794
5578492
5614283
92764_at
92765_s_at
A_52_P114414
A_52_P666855
A_55_P1973233
A_55_P1973238
GE36674
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005078
GO:0005515
GO:0005524
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0005886
GO:0006468
GO:0007265
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0019901
GO:0019933
GO:0023052
GO:0031434
GO:0032587
GO:0032991
GO:0036211
GO:0042127
GO:0042995
GO:0043226
GO:0043231
GO:0043405
GO:0043410
GO:0046872
GO:0051087
GO:0051879
GO:0060090
GO:0071889
GO:0106310
GO:0140096
ILMN_1254652
ILMN_2849036
U43585_s_at
mMC002142
Participates
as a component of
KSR1:MARK3 [cytosol] (Mus musculus)
Other forms of this molecule
phospho-p-S311,S406 KSR1 [cytosol]
phospho-p-S311 KSR1 [cytosol]
phospho-p-S311,Y602 KSR1 [plasma membrane]
phospho-p-S311,Y602 KSR1 [cytosol]
Inferred From
KSR1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006532398.1
,
NP_038599.1
,
NP_001335136.1
Ensembl
ENSMUSG00000018334
,
ENSMUST00000018478
,
ENSMUSP00000018478
PRO
Q61097
MGI
105051
PDB
1KBE
,
1KBF
,
2LPE
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.632
3
UniProt:P63101 Ywhaz
3
14-3-3zeta [cytosol]
(R-MMU-206177)
Ywhaz [nucleoplasm]
(R-MMU-450469)
Ywhaz [cytosol]
(R-MMU-206099)
0.547
2
UniProt:P36507 MAP2K2
12
MAP2K2(1-10) [cytosol]
(R-HSA-5211334)
MAP2K2(11-400) [cytosol]
(R-HSA-5211337)
MAP2K2 C125S [cytosol]
(R-HSA-9652070)
MAP2K2 P128Q [cytosol]
(R-HSA-9652082)
MAP2K2 V35M [cytosol]
(R-HSA-9652086)
MAP2K2 Y134C [cytosol]
(R-HSA-9652089)
p-S222,S226-MAP2K2 [cytosol]
(R-HSA-169292)
MAP2K2 [cytosol]
(R-HSA-59504)
p-S,T-MAP2K2 [cytosol]
(R-HSA-109848)
MAP2K2 N126D [cytosol]
(R-HSA-9652079)
MAP2K2 L46F [cytosol]
(R-HSA-9652076)
MAP2K2 F57C [cytosol]
(R-HSA-9652073)
0.508
2
UniProt:Q02750 MAP2K1
20
MAP2K1(9-393) [cytosol]
(R-HSA-5211353)
MAP2K1(2-8) [cytosol]
(R-HSA-5211342)
MAP2K1 F53S [cytosol]
(R-HSA-9652034)
MAP2K1 D67N [cytosol]
(R-HSA-9652016)
MAP2K1 Q56P [cytosol]
(R-HSA-9652064)
MAP2K1 E203K [cytosol]
(R-HSA-9652023)
MAP2K1 V60E [cytosol]
(R-HSA-9652067)
MAP2K1 P124S [cytosol]
(R-HSA-9652062)
MAP2K1 Y130C [cytosol]
(R-HSA-9652101)
MAP2K1 C121S [cytosol]
(R-HSA-9652013)
MAP2K1 G128V [cytosol]
(R-HSA-9652047)
MAP2K1 F53L [cytosol]
(R-HSA-9652031)
MAP2K1 K57N [cytosol]
(R-HSA-9652050)
MAP2K1 K57T [cytosol]
(R-HSA-9652052)
MAP2K1 F53V [cytosol]
(R-HSA-9652038)
MAP2K1 D67Y [cytosol]
(R-HSA-9652019)
MAP2K1 G128D [cytosol]
(R-HSA-9652043)
MAP2K1 P124L [cytosol]
(R-HSA-9652056)
MAP2K1 F53Y [cytosol]
(R-HSA-9652041)
MAP2K1 L42_K57del [cytosol]
(R-HSA-9652026)
0.508
2
UniProt:P15056 BRAF
20
BRAF(1-380)-MACF1(600-7388)fusion [cytosol]
(R-HSA-6802402)
p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol]
(R-HSA-6802536)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
BRAF T244P [cytosol]
(R-HSA-9651165)
0.499
3
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