Reactome | Rmi1 [nucleoplasm]

Rmi1 [nucleoplasm]

Stable Identifier

R-MMU-5685949

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

RMI1, Q9D4G9

Locations in the PathwayBrowser

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Cell Cycle (Mus musculus)

- Cell Cycle Checkpoints (Mus musculus)
  - G2/M Checkpoints (Mus musculus)
    - G2/M DNA damage checkpoint (Mus musculus)
      - ATR phosphorylates TP53 (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)

DNA Repair (Mus musculus)

- DNA Double-Strand Break Repair (Mus musculus)
  - Homology Directed Repair (Mus musculus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Mus musculus)
      - HDR through Homologous Recombination (HRR) (Mus musculus)
        
        D-loop extension by DNA polymerases (Mus musculus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Homologous DNA Pairing and Strand Exchange (Mus musculus)
        
        CX3 complex binds D-loop structures (Mus musculus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Presynaptic phase of homologous DNA pairing and strand exchange (Mus musculus)
        
        BCDX2 complex stabilizes RAD51 filament (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Resolution of D-Loop Structures (Mus musculus)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Mus musculus)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Mus musculus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Mus musculus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        MUS81:EME1,EME2 cleaves D-loop (Mus musculus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        SPIDR binds BLM:TOP3A:RMI1:RMI2 (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2:SPIDR [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
      - HDR through Single Strand Annealing (SSA) (Mus musculus)
        
        Association of RAD51 with RAD52:DNA double-strand break ends (Mus musculus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Association of RAD52 with the RPA complex at resected DNA DSBs (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        ERCC1:XPF cleaves flaps generated by SSA (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        RAD52 promotes single strand annealing at resected DNA DSBs (Mus musculus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
      - Processing of DNA double-strand break ends (Mus musculus)
        
        ATR activation at DNA DSBs (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        ATR phosphorylates RPA2 (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Activation of CHEK1 at resected DNA DSBs (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Association of RPA complexes with ssDNA at resected DNA DSBs (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Binding of ATR:ATRIP to RPA at resected DNA DSBs (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        CHEK1 is recruited to resected DNA DSBs (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Mus musculus)
        
        3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        Long-range resection of DNA DSBs by EXO1 or DNA2 (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)
        
        3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Activity through Phosphorylation (Mus musculus)
        
        ATR phosphorylates TP53 (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
        
        DNA2:BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)
        
        Rmi1 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9D4G9

Gene Names

Rmi1

Reference Genes

BioGPS Gene:74386 Rmi1

ENSEMBL:ENSMUSG00000035367

ENSEMBL:ENSMUSG00000035367.10 Rmi1

KEGG Gene (Mus musculus):74386 Rmi1

Monarch:74386 Rmi1

NCBI Gene:74386 Rmi1

UCSC:Q9D4G9 Rmi1

Reference Transcript

Other Identifiers

10405628

10608422

1428625_a_at

1430805_s_at

1438573_at

1439248_at

1456696_x_at

160736_at

17287893

4364413

4416131

4431827

4504403

4543260

4797103

4866508

4870225

4913842

4931942

5037822

5121243

5133911

5145817

5213676

5258075

5276905

5297549

5385043

5555824

5586778

74386

A_51_P187665

A_55_P2118799

A_55_P2845096

GE39985

GO:0000166

GO:0000712

GO:0000724

GO:0002021

GO:0002023

GO:0003674

GO:0005634

GO:0005654

GO:0005694

GO:0006260

GO:0006281

GO:0006310

GO:0007059

GO:0009749

GO:0016604

GO:0022414

GO:0031422

GO:0035264

GO:0042593

GO:0043226

GO:0071139

GO:0140013

ILMN_1249493

aa692678_i_at

aa692678_s_at

mMC007364

Participates

as a component of

BLM:TOP3A:RMI1:RMI2 [nucleoplasm] (Mus musculus)

Inferred From

RMI1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001161720.1, XP_006517483.1, NP_083180.3

Ensembl

ENSMUST00000224479, ENSMUSP00000153621, ENSMUSP00000153675, ENSMUST00000225828, ENSMUST00000225815, ENSMUST00000042450, ENSMUSG00000035367, ENSMUSP00000041035, ENSMUSP00000153050

PRO

Q9D4G9

MGI

1921636

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