Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-Foxo3 [cytosol]
Stable Identifier
R-MMU-5687014
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
p-S215 FOXO3, Q9WVH4
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK6/MAPK4 signaling (Mus musculus)
p-S215 FOXO3 translocates to the nucleus (Mus musculus)
phospho-Foxo3 [cytosol] (Mus musculus)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)
phospho-Foxo3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9WVH4 Foxo3
Gene Names
Foxo3, Fkhr2, Foxo3a
Chain
chain:1-672
Reference Genes
BioGPS Gene:56484 Foxo3
KEGG:mmu:56484 Foxo3
Monarch:56484 Foxo3
NCBI Gene:56484 Foxo3
UCSC:Q9WVH4 Foxo3
Reference Transcript
RefSeq:XM_006512806.1 Foxo3
RefSeq:NM_019740.2 Foxo3
Other Identifiers
10368886
10368888
1434831_a_at
1434832_at
1444226_at
1450236_at
17240529
4312122
4346244
4357014
4429764
4519412
4575394
4623230
4637115
5080451
5189583
5232980
5341345
5473299
5490721
5611582
56484
92958_at
A_51_P145507
A_52_P373852
A_55_P2129309
A_55_P2150896
A_55_P2506540
A_55_P2735425
A_65_P08314
GE120257
GO:0000122
GO:0000976
GO:0000978
GO:0000981
GO:0001221
GO:0001227
GO:0001228
GO:0001542
GO:0001544
GO:0001547
GO:0001556
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005759
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006390
GO:0006417
GO:0006915
GO:0008013
GO:0009410
GO:0010508
GO:0012501
GO:0014737
GO:0016020
GO:0019901
GO:0022414
GO:0030330
GO:0030336
GO:0031490
GO:0031667
GO:0032991
GO:0033209
GO:0034246
GO:0034599
GO:0042149
GO:0042593
GO:0042594
GO:0043065
GO:0043226
GO:0043525
GO:0043565
GO:0045591
GO:0045648
GO:0045665
GO:0045893
GO:0045944
GO:0048854
GO:0060070
GO:0070542
GO:0071333
GO:0071386
GO:0071456
GO:0071548
GO:0090090
GO:0090571
GO:0097150
GO:0097192
GO:0140110
GO:1901300
GO:1902895
GO:1903428
GO:1904646
GO:1990090
GO:1990785
GO:1990837
GO:2000177
GO:2000353
GO:2000377
ILMN_2439078
ILMN_2501865
ILMN_2690574
ILMN_2772652
aa710880_at
mMC003480
mMC014692
mMC014829
Participates
as an output of
p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)
as an input of
p-S215 FOXO3 translocates to the nucleus (Mus musculus)
Other forms of this molecule
phospho-Foxo3 [nucleoplasm]
Foxo3 [cytosol]
Foxo3 [mitochondrial matrix]
Foxo3 [mitochondrial matrix]
Foxo3 [nucleoplasm]
Foxo3 [nucleoplasm]
phospho-Foxo3 [cytosol]
phospho-Foxo3 [nucleoplasm]
Foxo3 [nucleoplasm]
Inferred From
p-S215 FOXO3 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 215 (in Homo sapiens)
Coordinate
215
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_062714.1
,
XP_006512869.1
ENSEMBL
ENSMUST00000056974
,
ENSMUSP00000101141
,
ENSMUST00000105502
,
ENSMUSP00000050683
,
ENSMUST00000175881
,
ENSMUSP00000135380
PRO
Q9WVH4
MGI
1890081
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Foxp3 ENSMUSG00000039521
0.564
2
UniProt:Q8WTS6 SETD7
1
SETD7 [nucleoplasm]
(R-HSA-1183221)
0.544
5
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text