Reactome | Asxl1 [nucleoplasm]

Asxl1 [nucleoplasm]

Stable Identifier

R-MMU-5689645

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

ASXL1, P59598

Locations in the PathwayBrowser

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Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Deubiquitination (Mus musculus)
    - UCH proteinases (Mus musculus)
      - BAP1 binds BAP1-interacting complex (Mus musculus)
        
        BAP1-interacting complex [nucleoplasm] (Mus musculus)
        
        BAP1-interacting core complex [nucleoplasm] (Mus musculus)
        
        ASXL1,ASXL2 [nucleoplasm] (Mus musculus)
        
        Asxl1 [nucleoplasm] (Mus musculus)
        
        BAP1:BAP1-interacting complex [nucleoplasm] (Mus musculus)
        
        BAP1-interacting complex [nucleoplasm] (Mus musculus)
        
        BAP1-interacting core complex [nucleoplasm] (Mus musculus)
        
        ASXL1,ASXL2 [nucleoplasm] (Mus musculus)
        
        Asxl1 [nucleoplasm] (Mus musculus)
      - Histone H2A is dubiquitinated by the PR-DUB complex (Mus musculus)
        
        PR-DUB complex [nucleoplasm] (Mus musculus)
        
        PR-DUB core complex [nucleoplasm] (Mus musculus)
        
        ASXL1,ASXL2 [nucleoplasm] (Mus musculus)
        
        Asxl1 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P59598

Gene Names

Asxl1

Reference Genes

BioGPS Gene:228790 Asxl1

ENSEMBL:ENSMUSG00000042548

Monarch:228790 Asxl1

NCBI Gene:228790 Asxl1

UCSC:P59598 Asxl1

Reference Transcript

RefSeq:NM_001039939.1 Asxl1

Other Identifiers

104246_at

104261_at

10477311

116882_at

1434561_at

1435077_at

1458380_at

17377940

228790

4342739

4431228

4470585

4484097

4519425

4540409

4602563

4641504

4659873

4684824

4839301

4868475

4889025

4890847

4926741

4971525

5010482

5013659

5063924

5099677

5106141

5164670

5171678

5258338

5266116

5310537

5336170

5337789

5412734

5513070

5570580

5593395

A_52_P123238

A_52_P549405

A_55_P1994052

GE1400705

GO:0000902

GO:0003007

GO:0003677

GO:0003682

GO:0003713

GO:0005515

GO:0005634

GO:0006325

GO:0006355

GO:0009887

GO:0010888

GO:0030097

GO:0032526

GO:0035359

GO:0035517

GO:0035564

GO:0042974

GO:0042975

GO:0043226

GO:0045599

GO:0045944

GO:0046872

GO:0048386

GO:0048534

GO:0048538

GO:0048539

GO:0048856

GO:0048872

GO:0060090

GO:0060348

GO:0060430

GO:0072015

GO:0140110

ILMN_1215405

ILMN_2492864

ILMN_2527760

W41911_s_at

aa273306_at

aa273306_g_at

mMC017742

mMC020326

Participates

as a member of

ASXL1,ASXL2 [nucleoplasm] (Mus musculus)

Inferred From

ASXL1 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSP00000105413, ENSMUST00000109790

PRO

P59598

GlyGen

P59598

MGI

2684063

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P10276 RARA	3	RARA [nucleoplasm] (R-HSA-446164) polySUMO2-K166,K171,K399-RARA [nucleoplasm] (R-HSA-4341042) SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm] (R-HSA-5334830)	0.61	4
UniProt:Q15788 NCOA1	3	NCOA1 [nucleoplasm] (R-HSA-442496) NCOA1 (868-1441) [nucleoplasm] (R-HSA-5603230) monoSUMO1-K732,K774-NCOA1 [nucleoplasm] (R-HSA-4085291)	0.544	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.508	2
UniProt:P28700 Rxra	5	RXRA [cytosol] (R-MMU-9619757) phospho-p-S21-RXRA [nucleoplasm] (R-MMU-5334811) monoSUMO1-K108-RXRA [nucleoplasm] (R-MMU-4341130) Rxra [nucleoplasm] (R-MMU-442483) RXRA [nucleoplasm] (R-MMU-381319)	0.508	2