Reactome | (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle]

(Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle]

Stable Identifier

R-MMU-5689724

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

COPII-coated ER to Golgi transport vesicle

Synonyms

P97821

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Asparagine N-linked glycosylation (Mus musculus)
    - Transport to the Golgi and subsequent modification (Mus musculus)
      - ER to Golgi Anterograde Transport (Mus musculus)
        
        COPII-mediated vesicle transport (Mus musculus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        Vesicle budding (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - ER to Golgi Anterograde Transport (Mus musculus)
    - COPII-mediated vesicle transport (Mus musculus)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
      - COPII coat binds TRAPPCII and RAB1:GDP (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
      - CSNK1D phosphorylates SEC23 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
      - Nucleotide exchange on RAB1 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
      - Vesicle budding (Mus musculus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Mus musculus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Mus musculus)

External Reference Information

External Reference

UniProt:P97821

Reference Genes

BioGPS Gene:13032

ENSEMBL:ENSMUSG00000030560

KEGG:mmu:13032

Monarch:13032

NCBI Gene:13032

UCSC:P97821

Reference Transcript

RefSeq:NM_009982.5

Other Identifiers

101019_at

101020_at

10554789

13032

1416382_at

1437939_s_at

1446834_at

166259_f_at

17480018

4329640

4389018

4478633

4512515

4596205

4682639

4686538

4708795

4955141

4964936

5009689

5030054

5031233

5077709

5173189

5228034

5234570

5339750

5343071

5388318

5416869

5473887

5532528

AA288280_s_at

A_52_P195839

A_55_P2072005

A_65_P05835

GE1447871

GE35270

GO:0001913

GO:0002376

GO:0003824

GO:0004197

GO:0004252

GO:0005615

GO:0005654

GO:0005737

GO:0005764

GO:0005773

GO:0005813

GO:0005815

GO:0006508

GO:0006915

GO:0008234

GO:0008239

GO:0012501

GO:0016505

GO:0016787

GO:0019902

GO:0030312

GO:0031012

GO:0031404

GO:0031642

GO:0042802

GO:0043226

GO:0043231

GO:0051087

GO:0051603

GO:0062023

GO:0098772

GO:0140096

GO:1903052

GO:1903980

GO:2001235

ILMN_1238486

ILMN_2681965

ILMN_3008858

ILMN_3008859

Msa.38948.0_s_at

mMC016906

u89269_s_at

Participates

as a member of

glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Mus musculus)

Other forms of this molecule

CTSC(25-134) [lysosomal lumen]

(Glc)3(GlcNAc)2(Man)9-CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane]

(Glc)3(GlcNAc)2(Man)9-CTSC [endoplasmic reticulum lumen]

CTSC(25-134) [extracellular region]

CTSC(25-134) [azurophil granule lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

ENSEMBL

ENSMUSG00000030560, ENSMUST00000032779, ENSMUSP00000032779

ZINC - Substances

CATC_MOUSE

ZINC target

P97821

PRO

P97821

GlyGen

P97821

MGI

109553

ZINC - Predictions - Purchasable

CATC_MOUSE

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