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PAR-UV-DDB [nucleoplasm]
Stable Identifier
R-MMU-5696649
Type
Complex
Species
Mus musculus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Mus musculus)
Nucleotide Excision Repair (Mus musculus)
Global Genome Nucleotide Excision Repair (GG-NER) (Mus musculus)
DNA Damage Recognition in GG-NER (Mus musculus)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Dual Incision in GG-NER (Mus musculus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Formation of Incision Complex in GG-NER (Mus musculus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Mus musculus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
CHD1L is recruited to GG-NER site (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Formation of the pre-incision complex in GG-NER (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
RNF111 ubiquitinates SUMOylated XPC (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Recruitment of XPA and release of CAK (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
SUMOylation of XPC (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
TFIIH binds GG-NER site to form a verification complex (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CUL4 [nucleoplasm]
(Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm]
(Mus musculus)
RBX1 [nucleoplasm]
(Mus musculus)
Participates
as an output of
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Mus musculus)
as a component of
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
Inferred From
PAR-UV-DDB [nucleoplasm]
(Homo sapiens)
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