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Ddb2 [nucleoplasm]
Stable Identifier
R-MMU-5696654
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
PAR-DDB2, Q99J79
Locations in the PathwayBrowser
Expand all
DNA Repair (Mus musculus)
Nucleotide Excision Repair (Mus musculus)
Global Genome Nucleotide Excision Repair (GG-NER) (Mus musculus)
DNA Damage Recognition in GG-NER (Mus musculus)
PARP1 or PARP2 PARylates DDB2 and autoPARylates (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Dual Incision in GG-NER (Mus musculus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Formation of Incision Complex in GG-NER (Mus musculus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Mus musculus)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
CHD1L is recruited to GG-NER site (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Formation of the pre-incision complex in GG-NER (Mus musculus)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
RNF111 ubiquitinates SUMOylated XPC (Mus musculus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Recruitment of XPA and release of CAK (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
SUMOylation of XPC (Mus musculus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
TFIIH binds GG-NER site to form a verification complex (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Mus musculus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Mus musculus)
PAR-UV-DDB [nucleoplasm] (Mus musculus)
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Ddb2 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q99J79
Gene Names
Ddb2
Reference Genes
BioGPS Gene:107986 Ddb2
ENSEMBL:ENSMUSG00000002109
ENSEMBL:ENSMUSG00000002109.15 Ddb2
KEGG Gene (Mus musculus):107986 Ddb2
Monarch:107986 Ddb2
NCBI Gene:107986 Ddb2
UCSC:Q99J79 Ddb2
Reference Transcript
RefSeq:NM_028119.5 Ddb2
Other Identifiers
10484999
107986
1425706_a_at
1436680_s_at
162751_at
17388196
4506860
4596155
4624376
4665322
4791091
4818767
4872716
5195739
5202827
5343078
5382984
5402518
5474712
5580567
5600075
A_55_P2092904
GE41391
GO:0000209
GO:0003677
GO:0003684
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006281
GO:0006289
GO:0006290
GO:0006974
GO:0009411
GO:0016567
GO:0016740
GO:0030054
GO:0031464
GO:0031465
GO:0032991
GO:0034644
GO:0036211
GO:0043226
GO:0044877
GO:0051865
GO:0070914
GO:0080008
GO:0090734
GO:0140096
ILMN_1229502
ILMN_2621160
ILMN_2655244
ILMN_2735575
mMC011676
Participates
as a component of
DDB1:PAR-DDB2 [nucleoplasm] (Mus musculus)
Other forms of this molecule
Ddb2 [nucleoplasm]
Ddb2 [nucleoplasm]
Inferred From
PAR-DDB2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
L-glutamyl-5-poly(ADP-ribose) at unknown position
PsiMod Name
L-glutamyl-5-poly(ADP-ribose)
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-glutamyl-5-poly(ADP-ribose).
Cross References
RefSeq
NP_082395.2
Ensembl
ENSMUST00000028696
,
ENSMUSG00000002109
,
ENSMUSP00000028696
PRO
Q99J79
MGI
1355314
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