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About
What is Reactome ?
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WRN [nucleoplasm]
Stable Identifier
R-MMU-67387
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
O09053
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G2/M Checkpoints (Mus musculus)
G2/M DNA damage checkpoint (Mus musculus)
ATR phosphorylates TP53 (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Chromosome Maintenance (Mus musculus)
Telomere Maintenance (Mus musculus)
Extension of Telomeres (Mus musculus)
Telomere C-strand (Lagging Strand) Synthesis (Mus musculus)
Processive synthesis on the C-strand of the telomere (Mus musculus)
Formation of the Flap Intermediate on the C-strand (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Removal of the Flap Intermediate from the C-strand (Mus musculus)
Removal of remaining Flap from the C-strand (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
DNA Repair (Mus musculus)
DNA Double-Strand Break Repair (Mus musculus)
Homology Directed Repair (Mus musculus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Mus musculus)
HDR through Homologous Recombination (HRR) (Mus musculus)
D-loop extension by DNA polymerases (Mus musculus)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Homologous DNA Pairing and Strand Exchange (Mus musculus)
CX3 complex binds D-loop structures (Mus musculus)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
D-loop formation mediated by PALB2, BRCA2 and RAD51 (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Presynaptic phase of homologous DNA pairing and strand exchange (Mus musculus)
BCDX2 complex stabilizes RAD51 filament (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Resolution of D-Loop Structures (Mus musculus)
Resolution of D-loop Structures through Holliday Junction Intermediates (Mus musculus)
Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Mus musculus)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
FIGNL1 binds RAD51 (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Ligation of DNA and formation of Holliday structures following repair synthesis (Mus musculus)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
MUS81:EME1,EME2 cleaves D-loop (Mus musculus)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Mus musculus)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
HDR through Single Strand Annealing (SSA) (Mus musculus)
Association of RAD51 with RAD52:DNA double-strand break ends (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Association of RAD52 with the RPA complex at resected DNA DSBs (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
ERCC1:XPF cleaves flaps generated by SSA (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
RAD52 promotes single strand annealing at resected DNA DSBs (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Processing of DNA double-strand break ends (Mus musculus)
ATR activation at DNA DSBs (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
ATR phosphorylates RPA2 (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Activation of CHEK1 at resected DNA DSBs (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Association of RPA complexes with ssDNA at resected DNA DSBs (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Binding of ATR:ATRIP to RPA at resected DNA DSBs (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
CHEK1 is recruited to resected DNA DSBs (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Mus musculus)
3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Long-range resection of DNA DSBs by EXO1 or DNA2 (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Activity through Phosphorylation (Mus musculus)
ATR phosphorylates TP53 (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Mus musculus)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Mus musculus)
DNA2:WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
EXO1:BLM,WRN [nucleoplasm] (Mus musculus)
BLM,WRN [nucleoplasm] (Mus musculus)
WRN [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:O09053
Reference Genes
BioGPS Gene:22427
ENSEMBL:ENSMUSG00000031583
ENSEMBL:ENSMUSG00000031583.14
KEGG Gene (Mus musculus):22427
Monarch:22427
NCBI Gene:22427
UCSC:O09053
Reference Transcript
RefSeq:XM_017312662.1
RefSeq:XM_006509091.3
RefSeq:NM_011721.4
RefSeq:NM_001122822.1
Other Identifiers
102891_at
10578071
113110_at
1425074_at
1425982_a_at
1450163_a_at
17508633
22427
4310432
4327512
4334803
4337426
4415209
4415744
4422428
4429836
4460408
4464670
4483283
4541387
4574257
4588951
4634104
4702591
4731322
4734651
4754353
4757998
4778879
4793624
4907961
4911461
4920952
4964466
5032898
5093087
5150863
5152331
5161263
5180635
5181974
5331826
5336896
5343184
5344649
5355867
5369138
5397170
5397704
5474329
5482479
5507502
A_52_P383506
A_52_P478236
A_55_P2160862
A_55_P2505195
A_55_P2736535
A_55_P2756465
GE36282
GO:0000166
GO:0000287
GO:0000400
GO:0000403
GO:0000405
GO:0000723
GO:0000724
GO:0000731
GO:0000781
GO:0003676
GO:0003677
GO:0003678
GO:0003682
GO:0003824
GO:0004386
GO:0004518
GO:0004527
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005730
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0006139
GO:0006259
GO:0006260
GO:0006268
GO:0006281
GO:0006284
GO:0006302
GO:0006310
GO:0006974
GO:0006979
GO:0008152
GO:0008340
GO:0008408
GO:0009267
GO:0009378
GO:0010225
GO:0012501
GO:0016607
GO:0016787
GO:0016887
GO:0030145
GO:0031297
GO:0032200
GO:0032392
GO:0032405
GO:0032508
GO:0040009
GO:0042803
GO:0042981
GO:0043138
GO:0043226
GO:0044237
GO:0044806
GO:0044877
GO:0046872
GO:0051880
GO:0061749
GO:0061820
GO:0061821
GO:0061849
GO:0070337
GO:0071480
GO:0090398
GO:0090399
GO:0098530
GO:0140097
GO:0140657
GO:1902570
GO:1905773
ILMN_1226576
ILMN_1244390
d86526_s_at
mMC021079
mMR029412
Participates
as a member of
BLM,WRN [nucleoplasm] (Mus musculus)
as a candidate of
BLM,WRN [nucleoplasm] (Mus musculus)
as a component of
DNA2:WRN [nucleoplasm] (Mus musculus)
This entity regulates
Positively
Removal of remaining Flap from the C-strand
(Mus musculus)
Other forms of this molecule
monoSUMO1-K356,K496,K898-WRN [nucleoplasm]
Inferred From
WRN [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_006509154.1
,
XP_017168151.1
,
NP_001116294.1
,
NP_035851.3
Ensembl
ENSMUST00000033990
,
ENSMUST00000033991
,
ENSMUSP00000033990
,
ENSMUSP00000033991
,
ENSMUSG00000031583
PRO
O09053
MGI
109635
PDB
2E6M
,
2E6L
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