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AQR [nucleoplasm]
Stable Identifier
R-MMU-6781960
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
Q8CFQ3
Locations in the PathwayBrowser
Expand all
DNA Repair (Mus musculus)
Nucleotide Excision Repair (Mus musculus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Mus musculus)
Dual incision in TC-NER (Mus musculus)
3' incision by ERCC5 (XPG) in TC-NER (Mus musculus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Mus musculus)
TC-NER incision complex [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Mus musculus)
TC-NER incision complex [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Mus musculus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Mus musculus)
TC-NER pre-incision complex [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
ERCC5 and RPA bind TC-NER site (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Formation of TC-NER Pre-Incision Complex (Mus musculus)
Assembly of the pre-incision complex in TC-NER (Mus musculus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
UVSSA:USP7 deubiquitinates ERCC6 (Mus musculus)
TC-NER pre-incision complex [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Mus musculus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Mus musculus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Mus musculus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Metabolism of RNA (Mus musculus)
Processing of Capped Intron-Containing Pre-mRNA (Mus musculus)
mRNA Splicing (Mus musculus)
mRNA Splicing - Major Pathway (Mus musculus)
Formation of the Spliceosomal Bact complex (Mus musculus)
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Spliceosomal Bact complex [nucleoplasm] (Mus musculus)
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Formation of the Spliceosomal C* complex (Mus musculus)
Spliceosomal C complex [nucleoplasm] (Mus musculus)
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Spliceosomal C* complex [nucleoplasm] (Mus musculus)
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Formation of the Spliceosomal P complex and exon ligation (Mus musculus)
Spliceosomal C* complex [nucleoplasm] (Mus musculus)
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
Spliceosomal P complex [nucleoplasm] (Mus musculus)
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
AQR [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8CFQ3
Reference Genes
BioGPS Gene:11834
ENSEMBL:ENSMUSG00000040383
ENSEMBL:ENSMUSG00000040383.17
KEGG Gene (Mus musculus):11834
Monarch:11834
NCBI Gene:11834
UCSC:Q8CFQ3
Reference Transcript
RefSeq:NM_001290788.1
RefSeq:NM_009702.3
Other Identifiers
103950_at
104549_at
10485989
11834
1430275_a_at
1430971_a_at
1433497_at
1452448_at
17389522
4329485
4341295
4351248
4354821
4405268
4462284
4463125
4500249
4528554
4538479
4580576
4605586
4635433
4696767
4701232
4723328
4750219
4805536
4852218
4862530
4890493
4896383
4953587
4972627
5056548
5103497
5149045
5161467
5163495
5291072
5292032
5317858
5329721
5334127
5354854
5395523
5424932
5480855
5500610
5522604
5528221
5547463
A_51_P100836
A_51_P245337
A_52_P157240
A_52_P20357
A_55_P2727908
A_66_P120481
GE33159
GO:0000166
GO:0000398
GO:0003723
GO:0003724
GO:0003727
GO:0003729
GO:0003824
GO:0004386
GO:0005524
GO:0005634
GO:0005654
GO:0005681
GO:0006397
GO:0008380
GO:0016071
GO:0016787
GO:0016887
GO:0034458
GO:0043226
GO:0071007
GO:0071013
GO:0140098
GO:0140657
ILMN_2676056
ILMN_2925196
U90333_s_at
aa018016_s_at
mMC004800
Participates
as a component of
PRP19-CDC5L related complex [nucleoplasm] (Mus musculus)
XAB2 complex [nucleoplasm] (Mus musculus)
Inferred From
AQR [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001277717.1
,
NP_033832.2
IntEnz
3.6.4.13
Ensembl
ENSMUSG00000040383
,
ENSMUST00000043160
,
ENSMUSP00000047157
PRO
Q8CFQ3
MGI
1276102
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