Reactome | Uba52 [nucleoplasm]

Uba52 [nucleoplasm]

Stable Identifier

R-MMU-6782503

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Ub-63-RPS27A(1-76), P62984

Locations in the PathwayBrowser

Expand all

DNA Repair (Mus musculus)

- Nucleotide Excision Repair (Mus musculus)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Mus musculus)
    - Formation of Incision Complex in GG-NER (Mus musculus)
      - RNF111 ubiquitinates SUMOylated XPC (Mus musculus)
        
        K63polyUb:C87-UBE2N:UBE2V2 [nucleoplasm] (Mus musculus)
        
        K63polyUb:C87-UBE2N [nucleoplasm] (Mus musculus)
        
        K63-Ub [nucleoplasm] (Mus musculus)
        
        Uba52 [nucleoplasm] (Mus musculus)
        
        Ub,SUMO,K63polyUb:XPC:RAD23:CETN2 [nucleoplasm] (Mus musculus)
        
        Ub,SUMO,K63polyUb:XPC [nucleoplasm] (Mus musculus)
        
        K63-Ub [nucleoplasm] (Mus musculus)
        
        Uba52 [nucleoplasm] (Mus musculus)

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Expression and Degradation (Mus musculus)
        
        Regulation of TP53 Degradation (Mus musculus)
        
        USP2 deubiquitinates MDM2,MDM4 (Mus musculus)
        
        PolyUb [nucleoplasm] (Mus musculus)
        
        K63polyUb [nucleoplasm] (Mus musculus)
        
        K63-Ub [nucleoplasm] (Mus musculus)
        
        Uba52 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:P62984 Uba52

Gene Names

Uba52, Ubcep2

Chain

chain:1-76, chain:77-128

Reference Genes

BioGPS Gene:22186 UBIQ

KEGG:mmu:22186 UBIQ

Monarch:22186 UBIQ

NCBI Gene:22186 UBIQ

UCSC:P62984 Uba52

Reference Transcript

Other Identifiers

10454805

10511342

10579302

10591208

10594904

10603009

1416624_a_at

1452701_x_at

17423006

22186

4397868

4442948

4462890

4555956

4561784

4573968

4585710

4605637

4618103

4631901

4640886

4673888

4794019

4798896

4828792

4943309

5074098

5193425

5199244

5298145

5344425

95907_at

A_51_P334571

A_55_P2006340

A_66_P138396

GO:0002181

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0015934

GO:0016567

GO:0019941

GO:0022625

GO:0031386

GO:0031625

GO:0043209

GO:0045202

GO:0098793

GO:0098794

GO:0140236

GO:0140242

GO:1990904

ILMN_1227046

ILMN_2515022

aa285406_s_at

mMC020790

Participates

as a member of

K63-Ub [nucleoplasm] (Mus musculus)

Other forms of this molecule

Uba52 [cytosol]

Ubiquitin (Uba52) [cytosol]

K48-Ubiquitin (Uba52) [cytosol]

Uba52 [nucleoplasm]

Ubiquitin (Uba52) [nucleoplasm]

K48-Ubiquitin (Uba52) [nucleoplasm]

Uba52 [cytosol]

Uba52 [nucleoplasm]

Uba52 [endoplasmic reticulum membrane]

Uba52 [cytosol]

Uba52 [mitochondrial outer membrane]

Uba52 [endosome membrane]

phospho-Uba52 [cytosol]

Uba52 [cytosol]

phospho-Uba52 [nucleoplasm]

Uba52 [cytosol]

Uba52 [mitochondrial outer membrane]

Uba52 [nucleoplasm]

Uba52 [endocytic vesicle membrane]

Inferred From

Ub-63-RPS27A(1-76) [nucleoplasm] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at 63 (in Homo sapiens)

Coordinate

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_001335156.1, NP_001335157.1, NP_063936.1, NP_001335158.1

ENSEMBL

ENSMUST00000081940, ENSMUSP00000137461, ENSMUSP00000086852, ENSMUST00000140679, ENSMUSP00000121149, ENSMUST00000129909, ENSMUST00000125184, ENSMUSP00000123263, ENSMUST00000135446, ENSMUSP00000120096, ENSMUSP00000123562, ENSMUSG00000090137, ENSMUSP00000080608, ENSMUSG00000068240, ENSMUST00000089430, ENSMUST00000165126

PRO

P62984

GlyGen

P62984

MGI

98887

PDB

7CPU, 7LS1, 7CPV, 7LS2, 6JWI, 6SWA, 3AI5