Reactome | Jmy [nucleoplasm]

Jmy [nucleoplasm]

Stable Identifier

R-MMU-6804247

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

PolyUb-JMY, Q9QXM1

Locations in the PathwayBrowser

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Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Activity through Methylation (Mus musculus)
        
        MDM2 ubiquitinates JMY (Mus musculus)
        
        Jmy [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9QXM1

Gene Names

Jmy

Reference Genes

BioGPS Gene:57748 Jmy

ENSEMBL:ENSMUSG00000021690

KEGG:mmu:57748 Jmy

Monarch:57748 Jmy

NCBI Gene:57748 Jmy

UCSC:Q9QXM1 Jmy

Reference Transcript

RefSeq:NM_021310.3 Jmy

Participates

as an output of

MDM2 ubiquitinates JMY (Mus musculus)

Other forms of this molecule

Jmy [nucleoplasm]

Inferred From

PolyUb-JMY [nucleoplasm] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [nucleoplasm]) at unknown position

Modification

PolyUb [nucleoplasm]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_067285.2

PRO

Q9QXM1

MGI

1913096

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q09472 EP300	5	EP300 [nucleoplasm] (R-HSA-381325) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) monoSUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306)	0.66	16
UniProt:Q9WV55	4	Vapa [cytosol] (R-MMU-9609920) Vapa [endoplasmic reticulum membrane] (R-MMU-429677) Vapa [plasma membrane] (R-MMU-6806269) Vapa [azurophil granule membrane] (R-MMU-6799364)	0.463	2

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