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HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]
Stable Identifier
R-MMU-6806977
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
Negative regulation of the PI3K/AKT network (Mus musculus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Activator:PI3K [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Activator:PI3K [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
RAS GEFs [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by MET (Mus musculus)
MET Receptor Activation (Mus musculus)
MET dimers autophosphorylate (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET activates PI3K/AKT signaling (Mus musculus)
Activated MET binds GAB1 (Mus musculus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
Activated MET binds GAB1 and GRB2 (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET bound PI3K generates PIP3 (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET phosphorylates GAB1 (Mus musculus)
HGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
Phosphorylated GAB1 recruits PI3K to MET (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET activates PTPN11 (Mus musculus)
GAB1 binds PTPN11 (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PTPN11 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET activates RAS signaling (Mus musculus)
Activated MET binds RANBP9 and SOS1 (Mus musculus)
HGF:p-4Y-MET dimer:RANBP10 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
Activated MET recruits GRB2-1:SOS1 (Mus musculus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET binds RANBP10 (Mus musculus)
HGF:p-4Y-MET dimer:RANBP10 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET binds SHC1-2 (Mus musculus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET phosphorylates SHC1-2 (Mus musculus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MUC20 binds MET and inhibits GRB2 binding (Mus musculus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Mus musculus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
SHC1-2 bound to MET recruits GRB2:SOS1 (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET activates STAT3 (Mus musculus)
MET phosphorylates STAT3 (Mus musculus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
STAT3 binds activated MET receptor (Mus musculus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET promotes cell motility (Mus musculus)
MET activates PTK2 signaling (Mus musculus)
MET phosphorylates PTK2 (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
PTK2 autophosphorylates (Mus musculus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
PTK2 binds activated MET (Mus musculus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
SRC phosphorylates PTK2 (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
p-Y397-PTK2 binds SRC (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET activates RAP1 and RAC1 (Mus musculus)
CRK,CRKL recruits RAC1 GEF to activated MET (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
DOCK7 activates RAC1 (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
GAB1 recruits CRK,CRKL to MET (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
RAPGEF1 activates RAP1 (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
RAPGEF1 binds CRK,CRKL (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET interacts with TNS proteins (Mus musculus)
MET binds TNS3 (Mus musculus)
HGF:p-4Y-MET dimer:TNS3 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET binds TNS4 (Mus musculus)
HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET receptor recycling (Mus musculus)
GGA3 associates with activated MET receptor (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
Negative regulation of MET activity (Mus musculus)
CBL binds MET (Mus musculus)
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:CBL,(HGF:p-Y1003,4Y-MET dimer:CBL) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
CBL monoubiquitinates activated MET (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
MET phosphorylates CBL (Mus musculus)
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:CBL,(HGF:p-Y1003,4Y-MET dimer:CBL) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
PTPN1 and PTPN2 dephosphorylate MET (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
PTPRJ dephosphorylates MET (Mus musculus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(Mus musculus)
Participates
as an input of
MET binds TNS3 (Mus musculus)
MET binds TNS4 (Mus musculus)
PTK2 binds activated MET (Mus musculus)
MUC20 binds MET and inhibits GRB2 binding (Mus musculus)
MET binds RANBP10 (Mus musculus)
PTPRJ dephosphorylates MET (Mus musculus)
PTPN1 and PTPN2 dephosphorylate MET (Mus musculus)
Activated MET binds GAB1 and GRB2 (Mus musculus)
Activated MET binds GAB1 (Mus musculus)
STAT3 binds activated MET receptor (Mus musculus)
MET binds SHC1-2 (Mus musculus)
Activated MET recruits GRB2-1:SOS1 (Mus musculus)
Activated MET binds RANBP9 and SOS1 (Mus musculus)
as a component of
HGF:p-4Y-MET dimer:TNS3 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Mus musculus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:RANBP10 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Mus musculus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Mus musculus)
as a member of
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Mus musculus)
as an output of
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Mus musculus)
MET phosphorylates STAT3 (Mus musculus)
MET dimers autophosphorylate (Mus musculus)
Inferred From
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]
(Homo sapiens)
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