Reactome | Ints11 [nucleoplasm]

Ints11 [nucleoplasm]

Stable Identifier

R-MMU-6807411

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

CPSF3L, Q9CWS4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        Ints11 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9CWS4

Gene Names

Ints11

Reference Genes

BioGPS Gene:71957 Ints11

ENSEMBL:ENSMUSG00000029034

KEGG:mmu:71957 Ints11

Monarch:71957 Ints11

NCBI Gene:71957 Ints11

UCSC:Q9CWS4 Ints11

Reference Transcript

Other Identifiers

10511207

1423964_at

17422764

4333351

4384894

4421571

4425833

4449961

4489366

4492195

4614116

4624669

4635791

4641083

4641384

4751860

4764719

4787018

4824440

4877164

4953001

5019964

5026509

5059377

5143918

5171485

5229945

5231069

5232481

5299437

5374558

5394746

5399812

5482818

5490420

5528213

5565540

5598717

71957

94053_at

A_51_P148163

A_55_P2036638

A_55_P2145307

GE102446

GE123816

GO:0003824

GO:0004521

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006351

GO:0006366

GO:0006368

GO:0016073

GO:0016180

GO:0016787

GO:0032039

GO:0034472

GO:0046872

GO:0140098

GO:0160232

GO:0160240

ILMN_1222271

ILMN_1249116

ILMN_2622487

mMC020386

mMR028294

Participates

as a component of

Integrator [nucleoplasm] (Mus musculus)

Inferred From

CPSF3L [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_006539258.1, NP_082296.1

ENSEMBL

ENSMUST00000030901, ENSMUSG00000029034, ENSMUSP00000030901

PRO

Q9CWS4

MGI

1919207

Cite Us!