Reactome | IntS13 [nucleoplasm]

IntS13 [nucleoplasm]

Stable Identifier

R-MMU-6807447

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

ASUN, Q8QZV7

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        Integrator [nucleoplasm] (Mus musculus)
        
        IntS13 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8QZV7

Gene Names

IntS13

Reference Genes

BioGPS Gene:71177 IntS13

ENSEMBL:ENSMUSG00000040250

KEGG:mmu:71177 IntS13

Monarch:71177 IntS13

NCBI Gene:71177 IntS13

UCSC:Q8QZV7 IntS13

Reference Transcript

RefSeq:NM_138757.2 IntS13

Other Identifiers

10549341

111814_at

111815_s_at

1419211_s_at

1429811_at

1455076_a_at

17472847

4335544

4413637

4423747

4446642

4579467

4629565

4655770

4757277

4777977

4786720

4806516

4816468

4827734

4844306

4901867

4936226

4955565

4970216

4970451

5015648

5023970

5025587

5169360

5234325

5287964

5292940

5314944

5331730

5346831

5358263

5418049

5438917

5554959

71177

A_55_P2519820

A_66_P109971

GE1435211

GO:0003674

GO:0005634

GO:0005654

GO:0005737

GO:0007010

GO:0007018

GO:0007052

GO:0007346

GO:0016073

GO:0016180

GO:0016604

GO:0022414

GO:0030317

GO:0032039

GO:0048870

GO:0051301

GO:0051642

GO:0080154

GO:0090435

GO:0140297

GO:0160232

GO:0160240

ILMN_1252267

ILMN_2694356

ILMN_2833356

mMC002964

Participates

as a component of

Integrator [nucleoplasm] (Mus musculus)

Inferred From

ASUN [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_620096.2

ENSEMBL

ENSMUSG00000040250, ENSMUST00000032427, ENSMUSP00000032427

PRO

Q8QZV7

MGI

1918427

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