Reactome | Ell2 [nucleoplasm]

Ell2 [nucleoplasm]

Stable Identifier

R-MMU-6807506

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

ELL2, Q3UKU1

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Mus musculus)
        
        LEC [nucleoplasm] (Mus musculus)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)
        
        Ell2 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q3UKU1

Gene Names

Ell2

Reference Genes

BioGPS Gene:192657 Ell2

ENSEMBL:ENSMUSG00000001542

ENSEMBL:ENSMUSG00000001542.8 Ell2

KEGG Gene (Mus musculus):192657 Ell2

Monarch:192657 Ell2

NCBI Gene:192657 Ell2

UCSC:Q3UKU1 Ell2

Reference Transcript

RefSeq:NM_138953.2 Ell2

Other Identifiers

103891_i_at

103892_r_at

10406254

1450744_at

1458569_at

17288699

192657

4456609

4459895

4557389

4591644

4601636

4616089

4616340

4646483

4839641

4865449

4915840

4957867

4958925

4969988

5002729

5031871

5148175

5173955

5275224

5490124

5536090

5586675

97704_at

AA414990_rc_g_at

A_51_P230507

A_52_P13305

A_55_P2928356

GE129190

GE1391381

GO:0000987

GO:0003677

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0006366

GO:0006368

GO:0008023

GO:0016073

GO:0032968

GO:0042795

GO:0043226

ILMN_2628426

Participates

as a member of

ELL,ELL2,ELL3 [nucleoplasm] (Mus musculus)

Inferred From

ELL2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_620403.2

Ensembl

ENSMUST00000001583, ENSMUSG00000001542, ENSMUSP00000001583

PRO

Q3UKU1

MGI

2183438

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