Reactome | Gbf1 [cytosol]

Gbf1 [cytosol]

Stable Identifier

R-MMU-6807751

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

GBF1, Q6DFZ1

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Asparagine N-linked glycosylation (Mus musculus)
    - Transport to the Golgi and subsequent modification (Mus musculus)
      - ER to Golgi Anterograde Transport (Mus musculus)
        
        COPI-mediated anterograde transport (Mus musculus)
        
        ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        ARFGAPs stimulate ARF GTPase activity (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        Active ARF recruits coatomer (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        GBF1 recruits ARF:GDP to the ERGIC (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        GBF1 stimulates ARF nucleotide exchange (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP recruits GBF1 to the ERGIC (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)

Vesicle-mediated transport (Mus musculus)

- Membrane Trafficking (Mus musculus)
  - ER to Golgi Anterograde Transport (Mus musculus)
    - COPI-mediated anterograde transport (Mus musculus)
      - ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
      - ARFGAPs stimulate ARF GTPase activity (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
      - Active ARF recruits coatomer (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
      - GBF1 recruits ARF:GDP to the ERGIC (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
      - GBF1 stimulates ARF nucleotide exchange (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
      - RAB1:GTP recruits GBF1 to the ERGIC (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Mus musculus)
    - Golgi-to-ER retrograde transport (Mus musculus)
      - COPI-dependent Golgi-to-ER retrograde traffic (Mus musculus)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)
        
        RAB:GTP recruits GBF1 to the Golgi membrane (Mus musculus)
        
        Gbf1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q6DFZ1

Gene Names

Gbf1

Reference Genes

BioGPS Gene:107338 Gbf1

ENSEMBL:ENSMUSG00000025224

ENSEMBL:ENSMUSG00000025224.17 Gbf1

KEGG Gene (Mus musculus):107338 Gbf1

Monarch:107338 Gbf1

NCBI Gene:107338 Gbf1

UCSC:Q6DFZ1 Gbf1

Reference Transcript

RefSeq:NM_178930.3 Gbf1

Other Identifiers

102003_at

10338168

10338244

10338421

10339456

10339710

10339729

10339753

10339774

10339961

10340005

10340036

10340181

10340237

10340432

10340633

10340647

10340823

10340860

10340979

10341010

10341242

10342021

10342360

10342537

10342830

10342913

10342983

10343063

10343383

10343701

10463557

107292_at

107338

1415709_s_at

1415757_at

1438207_at

17359925

4329310

4332931

4335628

4353729

4362340

4374052

4400915

4404682

4417238

4467166

4512782

4545982

4587818

4601240

4613531

4666904

4680207

4681066

4696329

4715112

4729570

4840414

4841440

4848921

4859535

4862751

4869077

4884493

4947904

5047331

5120660

5288969

5333594

5393082

5433591

5474048

5475671

5484805

5494068

5503250

5521259

5545295

5557675

5561827

5573822

5605442

A_51_P140597

A_51_P144712

A_55_P2377527

A_55_P2735460

GE1546435

GO:0000139

GO:0000278

GO:0002263

GO:0002376

GO:0005085

GO:0005515

GO:0005547

GO:0005737

GO:0005777

GO:0005783

GO:0005788

GO:0005793

GO:0005794

GO:0005795

GO:0005801

GO:0005802

GO:0005811

GO:0005829

GO:0006890

GO:0006895

GO:0007030

GO:0007163

GO:0007346

GO:0008289

GO:0015031

GO:0016020

GO:0016192

GO:0023052

GO:0030593

GO:0031252

GO:0032012

GO:0034067

GO:0042147

GO:0043226

GO:0048205

GO:0048870

GO:0051641

GO:0061024

GO:0061162

GO:0070973

GO:0080025

GO:0090166

GO:0097111

GO:0098586

GO:0098772

GO:1903409

GO:1903420

GO:2000008

ILMN_2726603

ILMN_2940559

mMC020278

Participates

as an output of

as an input of

as a component of

RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

Other forms of this molecule

Gbf1 [Golgi membrane]

Inferred From

GBF1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_849261.2

Ensembl

ENSMUST00000026254, ENSMUSP00000026254, ENSMUSG00000025224

MGI

1861607

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41542 Uso1	6	Uso1 [transport vesicle] (R-RNO-6808817) Uso1 [ER to Golgi transport vesicle membrane] (R-RNO-2422972) Uso1 [Golgi membrane] (R-RNO-2422968) Uso1 [ER to Golgi transport vesicle membrane] (R-RNO-2311338) Uso1 [Golgi membrane] (R-RNO-2167936) Uso1 [cytosol] (R-RNO-5685737)	0.508	3

Cite Us!