PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane

Stable Identifier
R-MMU-6809977
Type
Reaction [transition]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane
Formation of the complex with Sbf2 (Mtmr13) dramatically increases phosphatidylinositol-3-phosphatase catalytic activity of mouse Mtmr2 (Berger et al. 2006).
Literature References
PubMed ID Title Journal Year
16399794 Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

Volkmer, B, Berger, I, Tersar, K, Berger, P, Suter, U, Schaffitzel, C

Hum. Mol. Genet. 2006
Participants
Catalyst Activity

phosphatidylinositol-3-phosphatase activity of Mtmr2:Sbf2 Tetramer [cytosol]

Orthologous Events
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