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Cdt1 [nucleoplasm]
Stable Identifier
R-MMU-68536
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
CDT1, Q8R4E9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G1 phase and G1/S transition (Mus musculus)
G1/S Transition (Mus musculus)
Activation of the pre-replicative complex (Mus musculus)
CDT1 binds geminin (Mus musculus)
CDT1:GMNN [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 is displaced from the pre-replicative complex (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
MCM10:pre-replicative complex [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Mus musculus)
MCM10:pre-replicative complex [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDT1 binds geminin (Mus musculus)
CDT1:GMNN [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Orc1 removal from chromatin (Mus musculus)
Orc1 is phosphorylated by cyclin A/CDK2 (Mus musculus)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
DNA Replication (Mus musculus)
DNA Replication Pre-Initiation (Mus musculus)
Activation of the pre-replicative complex (Mus musculus)
CDT1 binds geminin (Mus musculus)
CDT1:GMNN [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 is displaced from the pre-replicative complex (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
MCM10:pre-replicative complex [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Mus musculus)
MCM10:pre-replicative complex [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Assembly of the pre-replicative complex (Mus musculus)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Mus musculus)
CDT1:GMNN [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDT1 binds geminin (Mus musculus)
CDT1:GMNN [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
Orc1 removal from chromatin (Mus musculus)
Orc1 is phosphorylated by cyclin A/CDK2 (Mus musculus)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
pre-replicative complex [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
Cdt1 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8R4E9
Gene Names
Cdt1
Reference Genes
BioGPS Gene:67177 Cdt1
ENSEMBL:ENSMUSG00000006585
ENSEMBL:ENSMUSG00000006585.4 Cdt1
KEGG Gene (Mus musculus):67177 Cdt1
Monarch:67177 Cdt1
NCBI Gene:67177 Cdt1
UCSC:Q8R4E9 Cdt1
Reference Transcript
RefSeq:NM_026014.3 Cdt1
Other Identifiers
10576140
1424143_a_at
1424144_at
17506418
4361903
4513085
4536516
4586480
4668274
4700227
4731354
4845133
5023110
5341199
5376987
5458278
5463432
67177
94024_at
A_51_P133612
GE121927
GO:0000076
GO:0000278
GO:0000775
GO:0000776
GO:0003677
GO:0003682
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006260
GO:0007049
GO:0007059
GO:0016604
GO:0023052
GO:0030174
GO:0033262
GO:0043226
GO:0045740
GO:0045786
GO:0051315
GO:0065003
GO:0070182
GO:0071163
GO:0072708
GO:0140014
GO:2000104
GO:2000105
ILMN_2730463
c76791_rc_s_at
mMC010749
Participates
as a component of
pre-replicative complex (Orc1-minus) [nucleoplasm] (Mus musculus)
CDT1:GMNN [nucleoplasm] (Mus musculus)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Mus musculus)
as an output of
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Mus musculus)
Cdt1 is displaced from the pre-replicative complex (Mus musculus)
as an input of
CDT1 binds geminin (Mus musculus)
Inferred From
CDT1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_080290.3
Ensembl
ENSMUSP00000006760
,
ENSMUST00000006760
,
ENSMUSG00000006585
PRO
Q8R4E9
MGI
1914427
PDB
2KLO
,
3A4C
,
2RQQ
,
2ZXX
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O88513
2
Gmnn [nucleoplasm]
(R-MMU-68585)
Gmnn [nucleoplasm]
(R-MMU-113554)
0.658
3
UniProt:P97311
1
MCM6 [nucleoplasm]
(R-MMU-68553)
0.508
2
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