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CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm]
Stable Identifier
R-MMU-68561
Type
Complex
Species
Mus musculus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G2/M Checkpoints (Mus musculus)
Activation of ATR in response to replication stress (Mus musculus)
Activation of claspin (Mus musculus)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
Loading of claspin onto DNA during replication origin firing (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G1 phase and G1/S transition (Mus musculus)
G1/S Transition (Mus musculus)
Activation of the pre-replicative complex (Mus musculus)
CDK and DDK associate with the Mcm10:pre-replicative complex (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
Cdc45 associates with the pre-replicative complex at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA polymerase alpha:primase binds at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA polymerase epsilon binds at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA Replication (Mus musculus)
DNA Replication Pre-Initiation (Mus musculus)
Activation of the pre-replicative complex (Mus musculus)
CDK and DDK associate with the Mcm10:pre-replicative complex (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
Cdc45 associates with the pre-replicative complex at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA polymerase alpha:primase binds at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
DNA polymerase epsilon binds at the origin (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CDK [nucleoplasm]
(Mus musculus)
DDK [nucleoplasm]
(Mus musculus)
MCM10:active pre-replicative complex [nucleoplasm]
(Mus musculus)
Participates
as an input of
Cdc45 associates with the pre-replicative complex at the origin (Mus musculus)
as an output of
CDK and DDK associate with the Mcm10:pre-replicative complex (Mus musculus)
as a component of
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Mus musculus)
Inferred From
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm]
(Homo sapiens)
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