Reactome | Snapc1 [nucleoplasm]

Snapc1 [nucleoplasm]

Stable Identifier

R-MMU-83726

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

SNAPC1, Q8K0S9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA polymerase II transcribes snRNA genes (Mus musculus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - Integrator complex processes the 3' end of snRNA (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Mus musculus)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Mus musculus)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Mus musculus)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
- RNA Polymerase III Transcription (Mus musculus)
  - RNA Polymerase III Transcription Initiation (Mus musculus)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Mus musculus)
      - Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Mus musculus)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Mus musculus)
        
        SNAPc [nucleoplasm] (Mus musculus)
        
        Snapc1 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8K0S9

Gene Names

Snapc1

Reference Genes

BioGPS Gene:75627 Snapc1

ENSEMBL:ENSMUSG00000021113

KEGG:mmu:75627 Snapc1

Monarch:75627 Snapc1

NCBI Gene:75627 Snapc1

UCSC:Q8K0S9 Snapc1

Reference Transcript

RefSeq:NM_178392.6 Snapc1

Other Identifiers

10396442

106867_at

1429335_at

1458400_at

163250_at

17276352

4321446

4357424

4540472

4632246

4648846

4652625

4757183

4799138

4868841

4877710

4929501

4996302

5014490

5084865

5151838

5238906

5252589

5290712

5298577

5354105

5449671

5516558

75627

A_51_P282268

A_52_P464524

A_52_P686405

GE1454022

GE1497532

GO:0003677

GO:0005634

GO:0005654

GO:0005730

GO:0016020

GO:0043226

ILMN_2446718

ILMN_2745849

mMC004956

mMC008145

Participates

as a component of

SNAPc [nucleoplasm] (Mus musculus)

Inferred From

SNAPC1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_848479.1

ENSEMBL

ENSMUSP00000021532, ENSMUSG00000021113, ENSMUST00000021532

PRO

Q8K0S9

MGI

1922877

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