Reactome | Thoc6 [nucleoplasm]

Thoc6 [nucleoplasm]

Stable Identifier

R-MMU-8849144

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

THOC6, Q5U4D9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA Polymerase II Transcription Termination (Mus musculus)
    - Cleavage of mRNA at the 3'-end (Mus musculus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)

Metabolism of RNA (Mus musculus)

- Processing of Capped Intron-Containing Pre-mRNA (Mus musculus)
  - Transport of Mature Transcript to Cytoplasm (Mus musculus)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Mus musculus)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Mus musculus)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Mus musculus)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Mus musculus)
        
        TREX (minus DDX39B) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
  - mRNA 3'-end processing (Mus musculus)
    - Cleavage of mRNA at the 3'-end (Mus musculus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
    - TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Mus musculus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
      - THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
    - mRNA polyadenylation (Mus musculus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc6 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q5U4D9

Gene Names

Thoc6

Reference Genes

BioGPS Gene:386612 Thoc6

ENSEMBL:ENSMUSG00000041319

ENSEMBL:ENSMUSG00000041319.15 Thoc6

KEGG Gene (Mus musculus):386612 Thoc6

Monarch:386612 Thoc6

NCBI Gene:386612 Thoc6

UCSC:Q5U4D9 Thoc6

Reference Transcript

Other Identifiers

10448292

1434827_at

17341521

386612

4335449

4509486

4659831

4689911

4721875

4761301

4782480

4793237

4904299

5028376

5035505

5040891

5042531

5090942

5094196

5098304

5380794

5593038

5616516

A_52_P631568

A_55_P2169849

A_55_P2615065

GO:0000346

GO:0000347

GO:0000445

GO:0000781

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006397

GO:0006406

GO:0006913

GO:0006915

GO:0007417

GO:0008380

GO:0012501

GO:0016071

GO:0016604

GO:0016607

GO:0043066

GO:0043226

GO:0046784

GO:0048856

GO:0051028

ILMN_1249706

ILMN_2778428

Participates

as a component of

THO complex [nucleoplasm] (Mus musculus)

Inferred From

THOC6 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001008425.1, XP_006524607.1

Ensembl

ENSMUST00000047436, ENSMUSG00000041319, ENSMUSP00000111153, ENSMUSP00000093239, ENSMUST00000115490, ENSMUST00000095579, ENSMUSP00000038137

PRO

Q5U4D9

MGI

2677480