Reactome | Thoc7 [nucleoplasm]

Thoc7 [nucleoplasm]

Stable Identifier

R-MMU-8849145

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

THOC7, Q7TMY4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - RNA Polymerase II Transcription Termination (Mus musculus)
    - Cleavage of mRNA at the 3'-end (Mus musculus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)

Metabolism of RNA (Mus musculus)

- Processing of Capped Intron-Containing Pre-mRNA (Mus musculus)
  - Transport of Mature Transcript to Cytoplasm (Mus musculus)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Mus musculus)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Mus musculus)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Mus musculus)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Mus musculus)
        
        TREX (minus DDX39B) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
  - mRNA 3'-end processing (Mus musculus)
    - Cleavage of mRNA at the 3'-end (Mus musculus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
    - TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Mus musculus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
      - THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
    - mRNA polyadenylation (Mus musculus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Mus musculus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Mus musculus)
        
        THO complex [nucleoplasm] (Mus musculus)
        
        Thoc7 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TMY4

Gene Names

Thoc7

Reference Genes

BioGPS Gene:66231 Thoc7

ENSEMBL:ENSMUSG00000053453

ENSEMBL:ENSMUSG00000053453.10 Thoc7

KEGG Gene (Mus musculus):66231 Thoc7

Monarch:66231 Thoc7

NCBI Gene:66231 Thoc7

UCSC:Q7TMY4 Thoc7

Reference Transcript

Other Identifiers

10417676

114291_at

1448461_a_at

160260_at

17303568

4316101

4593849

4618756

4652460

4953980

5225264

5240018

5422148

5444359

5444843

66231

A_52_P391660

A_55_P1999829

A_55_P2145706

GE40749

GO:0000346

GO:0000347

GO:0000445

GO:0000781

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006397

GO:0006406

GO:0006913

GO:0008380

GO:0016071

GO:0016607

GO:0043226

GO:0046784

GO:0051028

ILMN_2744641

mMC023763

Participates

as a component of

THO complex [nucleoplasm] (Mus musculus)

Inferred From

THOC7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001272709.1, NP_079711.1

Ensembl

ENSMUST00000065865, ENSMUSP00000065819, ENSMUSG00000053453

PRO

Q7TMY4

MGI

1913481