Reactome | Haus6 [cytosol]

Haus6 [cytosol]

Stable Identifier

R-MMU-8855196

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

HAUS6, Q6NV99

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - Recruitment of transition zone proteins (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus6 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q6NV99

Gene Names

Haus6

Reference Genes

BioGPS Gene:230376 Haus6

ENSEMBL:ENSMUSG00000038047

ENSEMBL:ENSMUSG00000038047.19 Haus6

KEGG Gene (Mus musculus):230376 Haus6

Monarch:230376 Haus6

NCBI Gene:230376 Haus6

UCSC:Q6NV99 Haus6

Reference Transcript

RefSeq:NM_173400.2 Haus6

Other Identifiers

100290_f_at

10514201

109501_at

110565_r_at

1429665_at

1455488_at

17426956

230376

4342697

4393766

4428121

4438202

4474423

4479391

4488375

4501495

4568621

4646666

4647990

4846196

4867207

4877975

4902388

4916136

4966748

4979520

4991666

5013871

5017378

5066756

5075399

5096346

5153116

5162193

5178846

5262387

5338932

5425379

5498015

5535501

5536138

5581611

99777_s_at

A_51_P288026

A_52_P86268

A_55_P2020876

A_66_P115719

GE109169

GE138600

GO:0000226

GO:0005813

GO:0005815

GO:0005856

GO:0007010

GO:0007059

GO:0007098

GO:0008017

GO:0008092

GO:0043226

GO:0051225

GO:0070652

GO:1990498

ILMN_1233478

ILMN_2443794

c76650_rc_at

mMC013216

mMR028099

Participates

as a component of

HAUS complex [cytosol] (Mus musculus)

Inferred From

HAUS6 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_775576.2

Ensembl

ENSMUST00000070607, ENSMUSP00000070504, ENSMUSG00000038047

MGI

1923389

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