Reactome | Haus1 [cytosol]

Haus1 [cytosol]

Stable Identifier

R-MMU-8855199

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

HAUS1, Q8BHX1

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
        
        basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - Recruitment of transition zone proteins (Mus musculus)
      - basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - basal body:transition zone proteins [cytosol] (Mus musculus)
        
        basal body [cytosol] (Mus musculus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        HAUS complex [cytosol] (Mus musculus)
        
        Haus1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BHX1

Gene Names

Haus1

Reference Genes

BioGPS Gene:225745 Haus1

ENSEMBL:ENSMUSG00000041840

ENSEMBL:ENSMUSG00000041840.9 Haus1

KEGG Gene (Mus musculus):225745 Haus1

Monarch:225745 Haus1

NCBI Gene:225745 Haus1

UCSC:Q8BHX1 Haus1

Reference Transcript

RefSeq:NM_146089.2 Haus1

Other Identifiers

10459844

1424955_at

17355538

225745

4380939

4388381

4475165

4511166

4546407

4566316

4617721

4672080

4847126

4895178

4994169

5487501

5542911

A_51_P170696

GE133267

GO:0000922

GO:0003674

GO:0005737

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005874

GO:0007010

GO:0007049

GO:0007059

GO:0007098

GO:0043226

GO:0051225

GO:0051301

GO:0070652

GO:1990498

ILMN_1250852

mMC001717

Participates

as a component of

HAUS complex [cytosol] (Mus musculus)

Inferred From

HAUS1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_666201.1

Ensembl

ENSMUSG00000041840, ENSMUST00000048192, ENSMUSP00000035826

PRO

Q8BHX1

MGI

2385076

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