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ubiquitinated cargo [plasma membrane]
Stable Identifier
R-MMU-8866252
Type
Set [DefinedSet]
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Clathrin-mediated endocytosis (Mus musculus)
BAR domain proteins recruit dynamin (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
Cargo recognition for clathrin-mediated endocytosis (Mus musculus)
Epsin family proteins bind ubiquitinated cargo (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
Clathrin recruits PIK3C2A (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
F- and N- BAR domain proteins bind the clathrin-coated pit (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Mus musculus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Mus musculus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Mus musculus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Mus musculus)
CLASP proteins:cargo [plasma membrane] (Mus musculus)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
ubiquitinated cargo [plasma membrane] (Mus musculus)
Participants
members
EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [plasma membrane]
(Mus musculus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane]
(Mus musculus)
Participates
as an input of
Epsin family proteins bind ubiquitinated cargo (Mus musculus)
as a component of
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Mus musculus)
Inferred From
ubiquitinated cargo [plasma membrane]
(Homo sapiens)
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