Creb3l2 translocates from the cytosol to the nucleus

Stable Identifier
R-MMU-8874322
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
General
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PNG
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Medium
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 | PPTX  | SBGN
Creb3l2 translocates from the cytosol to the nucleus
After cleavage by Mbtps2 the N-terminal cytoplasmic domain of Creb3l2 is released into the cytosol and traffics to the nucleus where it binds CRE-like elements in promoters of genes such as Sec23a (Kondo et al. 2007, Kondo et al. 2012).
Literature References
PubMed ID Title Journal Year
17178827 BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer

Imaizumi, K, Yoshinaga, K, Kanemoto, S, Saito, A, Ogata, M, Hara, H, Nara, S, Hino, S, Kondo, S, Yamashita, A, Murakami, T

Mol. Cell. Biol. 2007
22705851 Activation of OASIS family, ER stress transducers, is dependent on its stabilization

Iwamoto, H, Hino, SI, Oki, M, Nomura, Y, Miyagi, H, Urano, F, Saito, A, Kaneko, M, Izumi, S, Imaizumi, K, Kawasaki, N, Kanemoto, S, Kondo, S, Asada, R

Cell Death Differ. 2012
Participants
Input
Output
Orthologous Events
CREB3L2 translocates from the cytosol to the nucleus (Homo sapiens)
Authored
May, B  (2016-05-21)
Reviewed
Schröder, M  (2017-02-25)
Created
May, B  (2016-05-22)
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