Creb3l1 (Oasis) translocates from the cytosol to the nucleus

Stable Identifier
R-MMU-8874373
Type
Reaction [omitted]
Species
Mus musculus
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Creb3l1 (Oasis) translocates from the cytosol to the nucleus
Cleavage by Mbtps2 releases the N-terminal domain of Creb3l1 (Oasis) into the cytosol and it then traffics to the nucleus (Kondo et al. 2005, Murakami et al. 2006, Kondo et al. 2012).
Literature References
PubMed ID Title Journal Year
22705851 Activation of OASIS family, ER stress transducers, is dependent on its stabilization

Iwamoto, H, Hino, SI, Oki, M, Nomura, Y, Miyagi, H, Urano, F, Saito, A, Kaneko, M, Izumi, S, Imaizumi, K, Kawasaki, N, Kanemoto, S, Kondo, S, Asada, R

Cell Death Differ. 2012
16417584 Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress

Imaizumi, K, Kanemoto, S, Saito, A, Ogata, M, Wanaka, A, Kondo, S, Murakami, T

J. Neurochem. 2006
15665855 OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

Imaizumi, K, Tatsumi, K, Otori, K, Kanemoto, S, Iseki, K, Ogata, M, Wanaka, A, Kondo, S, Murakami, T

Nat. Cell Biol. 2005
Participants
Input
Output
Orthologous Events
CREB3L1 translocates from the cytosol to the nucleus (Homo sapiens)
Authored
May, B  (2016-05-22)
Reviewed
Schröder, M  (2017-02-25)
Created
May, B  (2016-05-23)
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