Creb3l1 (Oasis) translocates from the cytosol to the nucleus

Stable Identifier
Reaction [omitted]
Mus musculus
SVG |   | PPTX  | SBGN
Creb3l1 (Oasis) translocates from the cytosol to the nucleus

Cleavage by Mbtps2 releases the N-terminal domain of Creb3l1 (Oasis) into the cytosol and it then traffics to the nucleus (Kondo et al. 2005, Murakami et al. 2006, Kondo et al. 2012).

Literature References
PubMed ID Title Journal Year
16417584 Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress

Murakami, T, Kondo, S, Ogata, M, Kanemoto, S, Saito, A, Wanaka, A, Imaizumi, K

J. Neurochem. 2006
22705851 Activation of OASIS family, ER stress transducers, is dependent on its stabilization

Kondo, S, Hino, SI, Saito, A, Kanemoto, S, Kawasaki, N, Asada, R, Izumi, S, Iwamoto, H, Oki, M, Miyagi, H, Kaneko, M, Nomura, Y, Urano, F, Imaizumi, K

Cell Death Differ. 2012
15665855 OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

Kondo, S, Murakami, T, Tatsumi, K, Ogata, M, Kanemoto, S, Otori, K, Iseki, K, Wanaka, A, Imaizumi, K

Nat. Cell Biol. 2005
Orthologous Events
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