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phospho-Shc1 [cytosol]
Stable Identifier
R-MMU-8934452
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
p-S139,3Y-SHC1-1, P98083
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ERBB2 (Mus musculus)
SHC1 events in ERBB2 signaling (Mus musculus)
Activated PKC phosphorylates SHC1 (Mus musculus)
phospho-Shc1 [cytosol] (Mus musculus)
SHC1 binds PTPN12 (Mus musculus)
p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2:PTPN12 [cytosol] (Mus musculus)
phospho-Shc1 [cytosol] (Mus musculus)
phospho-Shc1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P98083-3 Shc1
Gene Names
Shc1, Shc, ShcA
Participates
as an input of
SHC1 binds PTPN12 (Mus musculus)
as a component of
p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2:PTPN12 [cytosol] (Mus musculus)
as an output of
Activated PKC phosphorylates SHC1 (Mus musculus)
Other forms of this molecule
p-Y-Shc1-3 [cytosol]
Shc1-3 [cytosol]
Shc1 [plasma membrane]
Shc1 [plasma membrane]
Shc1 [plasma membrane]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
Shc1 [cytosol]
Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [plasma membrane]
phospho-Shc1 [plasma membrane]
phospho-Shc1 [cytosol]
Shc1 [cytosol]
phospho-Shc1 [cytosol]
Inferred From
p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2 [cytosol]
(Homo sapiens)
p-S139,3Y-SHC1-1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 349 (in Homo sapiens)
Coordinate
349
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 350 (in Homo sapiens)
Coordinate
350
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 427 (in Homo sapiens)
Coordinate
427
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-serine at 139 (in Homo sapiens)
Coordinate
139
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q60631 Grb2
1
Grb2 [cytosol]
(R-MMU-443287)
0.899
8
UniProt:Q9JKF1
3
Iqgap1 [plasma membrane]
(R-MMU-381681)
Iqgap1 [secretory granule membrane]
(R-MMU-6804803)
Iqgap1 [cytosol]
(R-MMU-5626371)
0.65
5
UniProt:P35831
1
PTPN12 [cytosol]
(R-MMU-432933)
0.558
2
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