Il12b [endoplasmic reticulum lumen]

Stable Identifier
R-MMU-8950207
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
endoplasmic reticulum lumen
General
The cDNA coding for the p40 polypepide chain of porcine IL-12 (porcine Interlekuin-12 subunit A) was cloned using sets of primers derived from the bovine sequence recognizing the porcine sequence. For these experiments we used the porcine IL-12 p40 subunit which shares 80% identity and 88% similarity with the human form (BLASTP Alignment program). Porcine p40 contains cysteine residues at nine out of the 10 positions found in the human form.
Literature References
PubMed ID Title Journal Year
11054122 Protein disulfide isomerase-mediated cell-free assembly of recombinant interleukin-12 p40 homodimers

Vandenbroeck, K, Billiau, A, Alloza, I, Scott, CJ, Martens, E

Eur. J. Biochem. 2000
External Reference Information
External Reference
UniProt:P43432 Il12b
Gene Names
Il12b
Chain
signal peptide:1-22, chain:23-335
Reference Genes
BioGPS Gene:16160 Il12b
ENSEMBL:ENSMUSG00000004296.15 Il12b
KEGG Gene (Mus musculus):16160 Il12b
Monarch:16160 Il12b
NCBI Gene:16160 Il12b
UCSC:P43432 Il12b
Reference Transcript
Other Identifiers
100779_at
10375331
1419530_at
1449497_at
16160
17248654
4473136
4625988
4700243
4816786
4863452
4892466
4948660
4967025
5064697
5220062
5435897
A_55_P2741233
GE34632
GO:0001916
GO:0002230
GO:0002323
GO:0002376
GO:0002827
GO:0002860
GO:0002862
GO:0004896
GO:0005125
GO:0005126
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0005886
GO:0006954
GO:0007155
GO:0007166
GO:0008083
GO:0008283
GO:0009897
GO:0009986
GO:0010033
GO:0010224
GO:0012501
GO:0016020
GO:0016064
GO:0016477
GO:0019221
GO:0023052
GO:0030101
GO:0030154
GO:0031410
GO:0031904
GO:0032693
GO:0032700
GO:0032725
GO:0032729
GO:0032733
GO:0032735
GO:0032740
GO:0032760
GO:0032816
GO:0032819
GO:0032946
GO:0034393
GO:0035722
GO:0036211
GO:0042093
GO:0042098
GO:0042102
GO:0042104
GO:0042164
GO:0042509
GO:0042531
GO:0042802
GO:0042832
GO:0043226
GO:0043514
GO:0044877
GO:0045519
GO:0045672
GO:0045785
GO:0046982
GO:0048018
GO:0048662
GO:0048856
GO:0048870
GO:0050671
GO:0050709
GO:0050829
GO:0051135
GO:0051142
GO:0051607
GO:0060089
GO:0070743
GO:0071222
GO:0071346
GO:0098542
GO:0098772
GO:1900747
GO:1903588
IL12_P40_at
ILMN_2756639
M86671_s_at
mMC018187
Participates
as a component of
Other forms of this molecule
Il12b [extracellular region]
Il12b [cytosol]
Il12b [endosome lumen]
Il12b [Golgi lumen]
Il12b [late endosome lumen]
Il12b [endoplasmic reticulum lumen]
Il12b [extracellular region]
Cross References
RefSeq
Ensembl
PRO
MGI
PDB
Interactors (1)
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