Reactome | phospho-Il6st [plasma membrane]

phospho-Il6st [plasma membrane]

Stable Identifier

R-MMU-8950439

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-Y-IL6ST, Q00560

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q00560

Gene Names

Il6st

Reference Genes

BioGPS Gene:16195 Il6st

ENSEMBL:ENSMUSG00000021756

KEGG:mmu:16195 Il6st

Monarch:16195 Il6st

NCBI Gene:16195 Il6st

UCSC:Q00560 Il6st

Reference Transcript

RefSeq:NM_010560.3 Il6st

Other Identifiers

10407173

135888_at

1421239_at

1437303_at

1452843_at

1460295_s_at

16195

17289889

4324142

4372594

4373127

4415221

4464258

4491518

4507039

4645451

4649320

4760171

4793752

4884641

4888600

5070606

5072421

5093102

5156682

5182755

5240956

5261360

5261644

5286868

5292905

5306629

5339077

5396175

5429654

5442007

5447360

5470060

5480139

5569674

5616805

94345_at

98349_at

A_51_P473888

A_55_P2738837

GE35603

GE40064

GO:0004896

GO:0004897

GO:0004915

GO:0004921

GO:0004923

GO:0004924

GO:0005127

GO:0005138

GO:0005515

GO:0005886

GO:0005896

GO:0005900

GO:0005975

GO:0005977

GO:0006091

GO:0006629

GO:0006642

GO:0007165

GO:0008284

GO:0008593

GO:0009897

GO:0014911

GO:0015026

GO:0016020

GO:0019221

GO:0019838

GO:0019955

GO:0019970

GO:0019981

GO:0030296

GO:0030425

GO:0032809

GO:0034097

GO:0038154

GO:0038165

GO:0042102

GO:0042802

GO:0043025

GO:0043235

GO:0043524

GO:0044297

GO:0045121

GO:0045669

GO:0045747

GO:0048711

GO:0048856

GO:0048861

GO:0051481

GO:0060089

GO:0060576

GO:0070102

GO:0070106

GO:0070110

GO:0070120

GO:0097110

GO:0098772

ILMN_2452075

ILMN_2608184

X62646_s_at

aa122778_s_at

mMC006345

mMR029779

Participates

as a component of

p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (Mus musculus)

Other forms of this molecule

Il6st [extracellular region]

Il6st [plasma membrane]

phospho-Il6st [plasma membrane]

Inferred From

p-Y-IL6ST [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_034690.3

ENSEMBL

ENSMUSP00000064205, ENSMUST00000184311, ENSMUST00000070731, ENSMUSP00000139227, ENSMUST00000183663, ENSMUSP00000138836

PRO

Q00560

GlyGen

Q00560

MGI

96560

PDB

4GL9, 7Z0L, 2HMH, 2BBU, 6C5X, 8QY6, 8QY4, 8QY5

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O35718 Socs3	1	Socs3 [cytosol] (R-MMU-1169197)	0.747	6
UniProt:Q62120 Jak2	11	JAK2 [cytosol] (R-MMU-210620) phospho-p-Y1007-JAK2 [cytosol] (R-MMU-873799) Jak2 [cytosol] (R-MMU-205743) phospho-p-12Y-JAK2 [cytosol] (R-MMU-2586516) p-Y1007-Jak2 [cytosol] (R-MMU-997296) p-12Y-Jak2 [cytosol] (R-MMU-2586515) JAK2 [endosome lumen] (R-MMU-2002372) phospho-p-Y813-JAK2 [cytosol] (R-MMU-997248) phospho-p-JAK2 [cytosol] (R-MMU-210621) p-Jak2 [cytosol] (R-MMU-8950633) phospho-p-Y1007,Y1008-JAK2 [cytosol] (R-MMU-9005327)	0.623	4
UniProt:P97378 Il12rb2	3	p-Y800-Il12rb2 [plasma membrane] (R-MMU-9006473) phospho-Il12rb2 [plasma membrane] (R-MMU-8950376) Il12rb2 [plasma membrane] (R-MMU-447249)	0.471	2