Reactome | Stat4 [cytosol]

Stat4 [cytosol]

Stable Identifier

R-MMU-8950606

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

STAT4, P42228

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P42228 Stat4

Gene Names

Stat4

Chain

chain:1-749

Reference Genes

BioGPS Gene:20849 Stat4

KEGG Gene (Mus musculus):20849 Stat4

Monarch:20849 Stat4

NCBI Gene:20849 Stat4

Reference Transcript

RefSeq:NM_001308266.1 Stat4
RefSeq:NM_011487.5 Stat4

Participates

as an input of

STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Mus musculus)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Mus musculus)
STAT4 binds IL12RB2:IL12RB2 (Mus musculus)
STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Mus musculus)

as a component of

IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3:STAT4 [plasma membrane] (Mus musculus)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Mus musculus)
IL35:(IL12RB2:p-JAK2) dimer:STAT4 [plasma membrane] (Mus musculus)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2:2xSTAT4 [plasma membrane] (Mus musculus)

as a member of

STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Mus musculus)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Mus musculus)

Other forms of this molecule

p-Y693-Stat4 [cytosol]

Stat4 [cytosol]

phospho-Stat4 [nucleoplasm]

phospho-Stat4 [cytosol]

Inferred From

STAT4 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_035617.1, NP_001295195.1

PRO

P42228

MGI

103062

PDB

1BGF

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