The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds E2f1 gene promoter

Stable Identifier
R-MMU-8978989
Type
Reaction [binding]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
The complex of Hdac1, Rbl1 and E2f4 or Hdac1, Rbl2 and E2f4 or E2f5 binds E2f1 gene promoter
Experiments performed on mouse fibroblasts, including both NIH-3T3 cell line and embryonic fibroblasts, have shown that in G0 and early G1 phase p130 (Rbl2) and p107 (Rbl1) form a complex with the histone deacetylase Hdac1 on the promoter of the E2f1 gene (Rayman et al. 2002).
Literature References
PubMed ID Title Journal Year
11959842 E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

Catchpole, S, Dynlacht, BD, te Riele, H, Dannenberg, JH, Watson, RJ, Rayman, JB, Indjeian, VB, Takahashi, Y

Genes Dev 2002
Participants
Orthologous Events
Authored
Reviewed
Created
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