Wwp1 polyubiquitinates Runx2

Stable Identifier
R-MMU-9008077
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Wwp1 polyubiquitinates Runx2

Once a complex between Runx2, Hivep3 (Shn3, Schnurri-3) and Wwp1 is formed in mouse cells, Wwp1, an E3 ubiquitin ligase, polyubiquitinates Runx2 (Jones et al. 2006).

Literature References
PubMed ID Title Journal Year
16728642 Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3

Jones, DC, Wein, MN, Oukka, M, Hofstaetter, JG, Glimcher, MJ, Glimcher, LH

Science 2006
Participants
Catalyst Activity

ubiquitin protein ligase activity of Runx2:Hivep3:Wwp1 [cytosol]

Orthologous Events
Authored
Reviewed
Created
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