Smurf1 polyubiquitinates Runx2

Stable Identifier
R-MMU-9009440
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Smurf1 polyubiquitinates Runx2

Recombinant mouse Smurf1 polyubiquitinates recombinant mouse Runx2 (Zhao et al. 2003).

Literature References
PubMed ID Title Journal Year
12738770 E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation

Zhao, M, Qiao, M, Oyajobi, BO, Mundy, GR, Chen, D

J. Biol. Chem. 2003
Participants
Catalyst Activity

ubiquitin protein ligase activity of Runx2:Smurf1 [cytosol]

Orthologous Events
Authored
Reviewed
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