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p-T497,T638,S657-Prkca [cytosol]
Stable Identifier
R-MMU-9010746
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated cell proliferation (Mus musculus)
DAG and Ca+2 bind to PKC and tether it to membrane (Mus musculus)
DAG:active PKC:Ca+2 [plasma membrane] (Mus musculus)
p-PKC [cytosol] (Mus musculus)
p-T497,T638,S657-Prkca [cytosol] (Mus musculus)
p-PKC [cytosol] (Mus musculus)
p-T497,T638,S657-Prkca [cytosol] (Mus musculus)
PKC autophosphorylates (Mus musculus)
p-PKC [cytosol] (Mus musculus)
p-T497,T638,S657-Prkca [cytosol] (Mus musculus)
PKC phosphorylates sphingosine kinase 1 (Mus musculus)
DAG:active PKC:Ca+2 [plasma membrane] (Mus musculus)
p-PKC [cytosol] (Mus musculus)
p-T497,T638,S657-Prkca [cytosol] (Mus musculus)
p-PKC [cytosol] (Mus musculus)
p-T497,T638,S657-Prkca [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P20444 Prkca
Gene Names
Prkca, Pkca
Chain
initiator methionine:, chain:2-672
Reference Genes
BioGPS Gene:18750 Prkca
KEGG:mmu:18750 Prkca
Monarch:18750 Prkca
NCBI Gene:18750 Prkca
UCSC:P20444 Prkca
Reference Transcript
RefSeq:NM_011101.3 Prkca
Participates
as a component of
Robo2:Akap5:p-T497,T638,S657-Prkca [plasma membrane] (Mus musculus)
as an input of
Akap5 recruits PKC to Robo2 (Mus musculus)
as a member of
p-PKC [cytosol] (Mus musculus)
Other forms of this molecule
PRKCA [nucleoplasm]
phospho-p-T497-PRKCA [cytosol]
phospho-p-T497,T638,S657-PRKCA [nucleoplasm]
PRKCA [plasma membrane]
phospho-pT497,T638,S657-PRKCA [plasma membrane]
PRKCA [cytosol]
Inferred From
p-T497,T638,S657-PRKCA [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 657
Coordinate
657
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 497
Coordinate
497
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 638
Coordinate
638
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_035231.2
ZINC - Substances
KPCA_MOUSE
ZINC target
P20444
PRO
P20444
MGI
97595
ZINC - Predictions - Purchasable
KPCA_MOUSE
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O08785 Clock
6
p-T451,T461-Clock [nucleoplasm]
(R-MMU-9920668)
Clock [cytosol]
(R-MMU-508720)
p-T451,T461-Clock [cytosol]
(R-MMU-9920658)
p-S-Clock [nucleoplasm]
(R-MMU-508670)
p-T451,T461,S440,S441,S446-Clock [nucleoplasm]
(R-MMU-9920662)
p-S,T451,T461,S440,S441,S446-Clock [nucleoplasm]
(R-MMU-9927976)
0.544
3
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