Reactome | Pik3ca [cytosol]

Pik3ca [cytosol]

Stable Identifier

R-MMU-9027214

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, PK3CA_MOUSE

Locations in the PathwayBrowser for interactor UniProt:P26450 Pik3r1

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External Reference Information

External Reference

UniProt:P42337 Pik3ca

Gene Names

Pik3ca

Chain

chain:1-1068

Reference Genes

BioGPS Gene:18706 Pik3ca

KEGG:mmu:18706 Pik3ca

Monarch:18706 Pik3ca

NCBI Gene:18706 Pik3ca

UCSC:P42337 Pik3ca

Reference Transcript

Other Identifiers

104461_at

10491331

105294_at

107411_at

1423144_at

1429434_at

1429435_x_at

1440054_at

1453134_at

1460326_at

17396677

18706

4309901

4316895

4320285

4338378

4355475

4367322

4382560

4439253

4549024

4581965

4625194

4657985

4681028

4709761

4786729

4803381

4835203

4969416

5031753

5042014

5051238

5092973

5154725

5200497

5320537

5351640

5352161

5355209

5411587

5485642

5595387

92452_at

A_52_P265002

A_52_P577116

A_65_P09318

GE34203

GO:0001525

GO:0001889

GO:0001932

GO:0003012

GO:0003824

GO:0004674

GO:0005515

GO:0005524

GO:0005737

GO:0005829

GO:0005886

GO:0005942

GO:0005943

GO:0005944

GO:0005975

GO:0006006

GO:0006325

GO:0006629

GO:0006909

GO:0007010

GO:0008286

GO:0010468

GO:0010629

GO:0014704

GO:0014823

GO:0014870

GO:0016192

GO:0016301

GO:0016303

GO:0016740

GO:0030027

GO:0030036

GO:0030295

GO:0030835

GO:0032869

GO:0035005

GO:0035994

GO:0036092

GO:0038084

GO:0038203

GO:0040014

GO:0043201

GO:0043457

GO:0043491

GO:0043524

GO:0043560

GO:0046854

GO:0046934

GO:0048009

GO:0048015

GO:0048661

GO:0048856

GO:0051897

GO:0055119

GO:0060612

GO:0071333

GO:0071464

GO:0071548

GO:0086003

GO:0097009

GO:0098772

GO:0106310

GO:0110053

GO:0140096

GO:0141068

GO:1903544

GO:1905477

GO:2000270

GO:2000811

ILMN_1234800

ILMN_2825201

Msa.241.0_at

Msa.241.0_g_at

aa420333_rc_at

mMC021854

Participates

as a component of

as an input of

as a member of

PI3K-catalytic subunit [cytosol] (Mus musculus)

Inferred From

PIK3CA [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_032865.2, XP_006535472.1, XP_006535473.1

ZINC - Investigational

PK3CA_MOUSE

ENSEMBL

ENSMUST00000108243, ENSMUSP00000029201, ENSMUSP00000103878, ENSMUST00000029201

ZINC - Substances

PK3CA_MOUSE

ZINC target

P42337

PRO

P42337

MGI

1206581

ZINC - Predictions - Purchasable

PK3CA_MOUSE

PDB

4A55

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01112 HRAS	20	S-Farn-Me-2xPalmS HRAS [plasma membrane] (R-HSA-9647912) proHRAS [cytosol] (R-HSA-9647765) S-Farn-proHRAS [endoplasmic reticulum membrane] (R-HSA-9647918) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS [plasma membrane] (R-HSA-62717) HRAS G12C [plasma membrane] (R-HSA-9656561) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G13R [plasma membrane] (R-HSA-6802368)	0.589	3
UniProt:P26450 Pik3r1	5	p-Y-Pik3r1 [cytosol] (R-MMU-9680631) Pik3r1 [cytosol] (R-MMU-3080572) Pi3k-p85 alpha [cytosol] (R-MMU-1295777) Pik3r1 [cytosol] (R-MMU-74789) Pik3r1 [plasma membrane] (R-MMU-198365)	0.573	7
UniProt:P41241	2	CSK [plasma membrane] (R-MMU-180499) CSK [cytosol] (R-MMU-203776)	0.499	2

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