Reactome | STEAP3 [endosome membrane]

STEAP3 [endosome membrane]

Stable Identifier

R-MMU-917861

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

endosome membrane

Synonyms

Q8CI59

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - TP53 Regulates Transcription of Cell Death Genes (Mus musculus)
        
        TP53 Regulates Transcription of Genes Involved in Cytochrome C Release (Mus musculus)
        
        STEAP3 binds BNIP3L (Mus musculus)
        
        STEAP3 [endosome membrane] (Mus musculus)
        
        STEAP3:BNIP3L [mitochondrial outer membrane] (Mus musculus)
        
        STEAP3 [endosome membrane] (Mus musculus)

Transport of small molecules (Mus musculus)

- Iron uptake and transport (Mus musculus)
  - Transferrin endocytosis and recycling (Mus musculus)
    - STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Mus musculus)
      - STEAP3,STEAP4 [endosome membrane] (Mus musculus)
        
        STEAP3 dimer [endosome membrane] (Mus musculus)
        
        STEAP3:FAD:Heme b [endosome membrane] (Mus musculus)
        
        STEAP3 [endosome membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8CI59

Reference Genes

BioGPS Gene:68428

ENSEMBL:ENSMUSG00000026389

KEGG:mmu:68428

Monarch:68428

NCBI Entrez Gene:68428

UCSC:Q8CI59

Reference Transcript

Participates

as an input of

STEAP3 binds BNIP3L (Mus musculus)

as a component of

Other forms of this molecule

STEAP3 [plasma membrane]

Inferred From

STEAP3 [endosome membrane] (Homo sapiens)

Cross References

RefSeq

NP_001078878.1, NP_573449.2

PRO

Q8CI59

GlyGen

Q8CI59

MGI

1915678

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22830 FECH	1	FECH [mitochondrial inner membrane] (R-HSA-189441)	0.527	2

© 2025 Reactome

Cite Us!