Foxo1 binds Ppargc1a

Stable Identifier
R-MMU-9623232
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Foxo1 binds Ppargc1a
Mouse Foxo1 forms a complex with mouse Ppargc1a (Pgc-1alpha). Binding of Foxo1 to Ppargc1a is inhibited by Akt-mediated phosphorylation of Foxo1 (Puigserver et al. 2003).
Literature References
PubMed ID Title Journal Year
12754525 Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

Walkey, CJ, Spiegelman, BM, Dong, H, Puigserver, P, Accili, D, Oriente, F, Rhee, J, Altomonte, J, Yoon, JC, Donovan, J, Kitamura, Y

Nature 2003
Participants
Input
Output
Orthologous Events
FOXO1 binds PPARGC1A (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-10-03)
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