Foxo1 and Nr3c1 bind Trim63 gene promoter

Stable Identifier
R-MMU-9625700
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Foxo1 and Nr3c1 bind Trim63 gene promoter

Recombinant mouse Foxo1 and recombinant mouse Nr3c1, activated by dexamethasone, bind to evolutionarily conserved forkhead box elements and glucocorticoid receptor elements (GREs) in the promoter of the mouse Trim63 gene, encoding an E3 ubiquitin ligase Murf1 (Waddell et al. 2008).

Literature References
PubMed ID Title Journal Year
18612045 The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

Waddell, DS, Baehr, LM, van den Brandt, J, Johnsen, SA, Reichardt, HM, Furlow, JD, Bodine, SC

Am. J. Physiol. Endocrinol. Metab. 2008
Participants
Orthologous Events
Authored
Reviewed
Created
Cite Us!